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04 Dec 23:44

04 Dec 23:42

Plot twist: Mitochondrial DNA can come from both parents

by Cathleen O'Grady
Mitochondria (red) and cell nucleus (blue) of two connective tissue cells prepared from mouse embryo.

Enlarge / Mitochondria (red) and cell nucleus (blue) of two connective tissue cells prepared from mouse embryo. (credit: Institute of Molecular Medicine I, University of Düsseldorf)

The vast majority of our DNA—the chromosomes in the nucleus of each cell—is just what you’d expect: a mix of genetic material from both mother and father. But mitochondria are an exception. They contain a relatively tiny amount of DNA, and in nearly all mammals and even unicellular organisms, that DNA comes strictly from the mother. We've even used that fact to trace the spread of humanity around the globe.

But in 2002, researchers in Copenhagen reported a jaw-dropping finding. In an effort to work out why one of their patients had extreme fatigue during exercise despite seeming healthy in many respects, they started examining his mitochondria—the energy-generating power stations living in each cell. What they found floored them: the man had mitochondrial DNA (mtDNA) that matched both his father's and his mother's.

Since 2002, no other cases of paternally inherited mtDNA have been reported in humans, despite several research groups actively looking. But a paper in this week’s PNAS reports mtDNA inherited from both parents in 17 different people from three families. This kind of inheritance is still extremely rare and seems potentially linked to mitochondrial disease, but the robust confirmation of it in humans is huge news for biology and medicine.

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04 Dec 23:37

One Little Ant

by Reza

04 Dec 23:34

Not Understanding

by Doug

Not Understanding

My school theme week continues!

04 Dec 23:33

Aunt (Part2)

by Lunarbaboon

04 Dec 23:28

How to Embrace Change

by Scott Meyer
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I’ve blathered before about how my nephews’ Christmas lists are the stuff of science fiction. VR headsets, hoverboards, 3D printers, that kinda thing. This year is different, I don’t know if it’s because they’re older or it’s just how things progress, but this year they seem to be asking for videogames for consoles they already own and new copies of things they already own and have broken, which is pretty much what I was asking for at their age.

Had an interesting discussion with one of their parents about how many of the things they want are primarily sold digitally, so most of the things that get wrapped up and put under the tree are clothing, which I think we can all agree, were always the least satisfying things to unwrap.

As always, thanks for using my Amazon Affiliate links (USUKCanada).

02 Dec 23:24

Algebra

by Doug

Algebra

I’m on the road, visiting schools and talking with kids about comics! So I’ll be posting my comics a little differently this week!

02 Dec 10:06

How to Give Somebody the Respect They Deserve

by Scott Meyer
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I stand by my position on Steve Jobs. He didn’t invent anything but his own public image, but he had tremendous taste and high standards, and we have all benefited from them.

As always, thanks for using my Amazon Affiliate links (USUKCanada).

26 Nov 14:39

Saturday Morning Breakfast Cereal - Exposure

by tech@thehiveworks.com


Click here to go see the bonus panel!

Hovertext:
I support all public funding for research which benefits me directly.


Today's News:
04 Nov 06:02

Knights and Knaves

https://www.oglaf.com/knightsandknaves/

04 Nov 06:01

Comic for October 07, 2018

by Scott Adams
04 Nov 06:01

Tudo mato

by Will Tirando

04 Nov 05:59

Conservadores da Planolândia

by brunomaron
04 Nov 05:58

E se acham o máximo

by Will Tirando

04 Nov 05:57

Stack-doubt

by CommitStrip

12 Oct 19:56

Comic for October 04, 2018

by Scott Adams
12 Oct 19:56

The Mightier

by itsthetie

12 Oct 19:55

Data Pipeline

"Is the pipeline literally running from your laptop?" "Don't be silly, my laptop disconnects far too often to host a service we rely on. It's running on my phone."
12 Oct 19:51

City in Color

by Grant

This comic appears in the latest issue of The Believer magazine. Thanks to art director Kristen Radtke! 

12 Oct 19:48

Saturday Morning Breakfast Cereal - Rise of the Machines

by tech@thehiveworks.com
12 Oct 19:46

The Frankfurt Four







Turns out Heraclitus was right. Like he said, fire is awesome, or something like that.
07 Oct 19:35

Comic for 2018.09.26

by Emily Explosm  |  2018.09.24
07 Oct 16:52

Sunrises

by Grant
07 Oct 16:51

Good or Bad

by Reza

07 Oct 16:51

Bad Opinions

I thought of another bad opinion! I couldn't find anyone who expressed it specifically, but still, the fact that I can so easily imagine it is infuriating! I'm gonna tell everyone about it!
07 Oct 16:49

Saturday Morning Breakfast Cereal - Cure

by tech@thehiveworks.com


Click here to go see the bonus panel!

Hovertext:
Also effective against consumption, the ague, brain fever, dropsy, and Unspeakable Lady Problems.


Today's News:
30 Sep 21:08

funfactcomics:If you were wondering why everyone has been acting...





funfactcomics:

If you were wondering why everyone has been acting so weird..

30 Sep 21:06

PINTURAS

by Saudades do Rio
Nicolao Antonio Facchinetti - Vista da Praia de Botafogo tomada do Morro do Pasmado - 1868
 

Nicolao Antonio Facchinetti - Vista de Copacabana tomada da Ladeira do Leme 1872
 

Que beleza a Baía da Guanabara nesta pintura de 1868, de autoria de Henri Nicolas Vinet. O Morro da Viúva sem nenhum prédio, o Pão de Açúcar sem a Urca a seus pés, a Enseada de Botafogo tranquila, tranquila. À direita vemos uma das três pontes de atracação que existiram na Praia de Botafogo (uma perto do Pasmado, outra na altura da Rua São Clemente e a terceira mais perto da atual Rua Marquês de Abrantes).
 

Sebastien Auguste Sisson - Hotel Pharoux 1850. O hotel pertencia ao parisiense Luiz Pharoux, um francês que veio se fixar na corte e que trouxe em suas instalações, requinte nada usual para os padrões da época. Ao final da década de 1860, Luiz Domingos Pharoux retornou à França e liquidou o prédio, onde mais tarde funcionaria a Casa de Saúde Drs. Catta Preta, Marinho & Werneck. Logo após ser vendido pelo fundador o Hotel Pharou virou o Hotel Waltz. Em 1864, o prédio foi ocupado pela Casa de Saúde N.S. da Glória e só depois pelo Dr. Catta Preta. Alguns anos e várias casas de saúde depois, o prédio voltou a abrigar um hotel, com o nome de Real (ou Royal) e em 1959 foi demolido para a construção da Perimetral.


Robert Streatfield - Lagoa 1850.  Segundo André Delacerda e Diogo Fagundes o Rio de Janeiro é uma cidade cheia de mistérios. Temos a Ibis do Pão de Açúcar e o rosto gigante da Pedra da Gávea. Mas, poucos sabem que a cerca de quase dois séculos atrás havia mais uma pedra que inspirava medo e mistério.

Era chamada de a Pedra Santa ou Pedra da Santa e ficava entre o Clube Piraquê e o bairro de Humaitá. Essa pedra tinha o formato de um rosto que olhava para dentro da Lagoa. Dizem que D. João tinha bastante medo de passar junto a este rosto, tanto que preferia chegar a região de barco. Não se sabe se a Pedra Santa foi esculpida por algum povo mais antigo ou era uma formação natural. Fato é que em 1837, um padre de nome Souto destruiu o grande rosto que deve ter rolado para o que então era a Lagoa Rodrigo de Freitas, já que boa parte do Jardim Botânico junto a Pedra foi aterrado posteriormente. O mesmo padre solicitou ao Instituto Histórico e Geográfico Brasileiro a destruição da Pedra da Gávea, mas sem êxito, e para nossa sorte que temos aquele monumento histórico natural preservado.

O caso envolve o Caminho da Cabeça, o "Rio da Cabeça" e a capela de Nossa Senhora da Cabeça, no final da Rua Faro. Pelas ultimas conclusões, esta pedra estava exatamente no sopé da atual Rua Faro, que era exatamente o Caminho da Cabeça. A Rua Jardim Botânico era a antiga Rua do Jardim, que mais próxima ao Humaitá passava a chamar-se Rua do Oliveira. A Lagoa chegava até esses caminhos como se vê na aquarela e em mapas antigos da Fazenda Nacional que ocupou a área antes de 1844.


26 Sep 16:18

Photo



25 Sep 15:36

Saturday Morning Breakfast Cereal - Batocrat

by tech@thehiveworks.com


Click here to go see the bonus panel!

Hovertext:
This is one of those comics that I mostly mean to just be funny, but will be interpreted as a direct political statement.


Today's News: