The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c02019
Melissa Lee
Shared posts
03 Sep 16:46
[ASAP] La Chimie Organique en France: Une Longue Tradition qui Persiste!
by Géraldine Masson(Associate Editor)
Sallustrau Antoine (Stro), pgecheverria and -1 others like this
28 Feb 21:14
[ASAP] Correction to “Graphene Nanoribbons Derived from Zigzag Edge-Encased Poly(para-2,9-dibenzo[bc,kl]coronenylene) Polymer Chains”
by Doreen Beyer, Shiyong Wang, Carlo A. Pignedoli, Jason Melidonie, Bingkai Yuan, Can Li, Jan Wilhelm, Pascal Ruffieux, Reinhard Berger, Klaus Müllen, Roman Fasel, Xinliang Feng
Journal of the American Chemical Society
DOI: 10.1021/jacs.9b01965
06 Dec 11:50
[ASAP] In Vitro Ligand Binding Kinetics Explains the Pharmacokinetics of [18F]FE-PE2I in Dopamine Transporter PET Imaging
by Siim Kukk, Olavi Loog, Jukka-Veli Hiltunen, Jaak Järv
ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.8b00504
15 Oct 00:28
[ASAP] Safety Evaluation of the Copper-Mediated Cross-Coupling of 2-Bromopyridines with Ethyl Bromodifluoroacetate
by Qiang Yang, Pablo J. Cabrera, Xiaoyong Li, Min Sheng, Nick X. Wang
Organic Process Research & Development
DOI: 10.1021/acs.oprd.8b00261
Melissa Lee likes this
27 Mar 19:52
[ASAP] Structure–Property Relationships for Tailoring Phenoxazines as Reducing Photoredox Catalysts
by Blaine G. McCarthy, Ryan M. Pearson, Chern-Hooi Lim, Steven M. Sartor, Niels H. Damrauer, Garret M. Miyake
Journal of the American Chemical Society
DOI: 10.1021/jacs.7b12074
23 Mar 17:47
[ASAP] Evidence for Ion-Templation During Macrocyclooligomerization of Depsipeptides
by Suzanne M. Batiste, Jeffrey N. Johnston
Journal of the American Chemical Society
DOI: 10.1021/jacs.7b13148
Oscar Verho, thomas liao likes this
21 Feb 00:45
Modular Access to Azepines by Directed Carbonylative C–C Bond Activation of Aminocyclopropanes
by Gang-Wei Wang and John F. Bower
Journal of the American Chemical Society
DOI: 10.1021/jacs.7b13087
Oscar Verho, wangqiang and 9 others like this
11 Feb 01:29
Electrochemical Difluoromethylarylation of Alkynes
by Peng Xiong, He-Huan Xu, Jinshuai Song and Hai-Chao Xu
Journal of the American Chemical Society
DOI: 10.1021/jacs.8b00391
06 Feb 14:53
[ASAP] Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
by Nicholas A. Meanwell
Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.7b01788
Oscar Verho, 大河弯弯的 and 4 others like this
28 Jan 01:33
Hot Paper: Dual Ligand-Enabled Nondirected C−H Olefination of Arenes
Hao Chen, Philipp Wedi, Tim Meyer, Dr. Ghazal Tavakoli and Dr. Manuel van Gemmeren
How many ligands does it take to change a bond? The Pd-catalyzed C−H olefination of arenes as the limiting reagents is reported. The combined action of two ligands, N-acetylglycine and a pyridine, enables this Fujiwara–Moritani reaction under steric/electronic control; traditionally this reaction required use of arenes as (co)solvents or of directing groups on the substrate.
Darren Poole likes this
18 Jan 15:40
High-Performance Oligomeric Catholytes for Effective Macromolecular Separation in Nonaqueous Redox Flow Batteries
by Koen H. Hendriks, Sophia G. Robinson, Miles N. Braten, Christo S. Sevov, Brett A. Helms, Matthew S. Sigman, Shelley D. Minteer and Melanie S. Sanford
ACS Central Science
DOI: 10.1021/acscentsci.7b00544
Melissa Lee likes this
11 Jan 01:42
Stereoselective Dynamic Cyclization of Allylic Azides: Synthesis of Tetralins, Chromanes, and Tetrahydroquinolines
by Matthew R. Porter, Rami M. Shaker, Cristian Calcanas and Joseph J. Topczewski
Journal of the American Chemical Society
DOI: 10.1021/jacs.7b11299
zhanglinli, longlenovo zheng and 3 others like this
10 Jan 20:32
Iron-Catalyzed Difluoromethylation of Arylzincs with Difluoromethyl 2-Pyridyl Sulfone
by Wenjun Miao, Yanchuan Zhao, Chuanfa Ni, Bing Gao, Wei Zhang and Jinbo Hu
Journal of the American Chemical Society
DOI: 10.1021/jacs.7b11976
03 Jan 16:09
Regioselective Halogenation of Arenes and Heterocycles in Hexafluoroisopropanol
by Ren-Jin Tang, Thierry Milcent and Benoit Crousse
The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.7b02920
19 Dec 19:26
N-Hydroxyphthalimide-Mediated Electrochemical Iodination of Methylarenes and Comparison to Electron-Transfer-Initiated C–H Functionalization
by Mohammad Rafiee, Fei Wang, Damian P. Hruszkewycz and Shannon S. Stahl
Journal of the American Chemical Society
DOI: 10.1021/jacs.7b09744
15 Dec 21:55
Open Access
  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Site-selective 18F fluorination of unactivated C-H bonds mediated by a manganese porphyrin
Chem. Sci., 2018, 9,1168-1172
DOI: 10.1039/C7SC04545J, Edge Article
DOI: 10.1039/C7SC04545J, Edge Article
Open Access  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Wei Liu, Xiongyi Huang, Michael S. Placzek, Shane W. Krska, Paul McQuade, Jacob M. Hooker, John T. Groves
A direct aliphatic C-H 18F labeling method using [18F]fluoride ion at inaccessible and unreactive sites is reported.
The content of this RSS Feed (c) The Royal Society of Chemistry
A direct aliphatic C-H 18F labeling method using [18F]fluoride ion at inaccessible and unreactive sites is reported.
The content of this RSS Feed (c) The Royal Society of Chemistry
Leuchtkaefer likes this
07 Dec 18:19
Cooperative CO2 Absorption Isotherms from a Bifunctional Guanidine and Bifunctional Alcohol
by Rachel Steinhardt, Stanley C. Hiew, Hemakesh Mohapatra, Du Nguyen, Zachary Oh, Richard Truong and Aaron Esser-Kahn
ACS Central Science
DOI: 10.1021/acscentsci.7b00418
04 Dec 21:49
Open Access
  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Organocatalytic nitrenoid transfer: metal-free selective intermolecular C(sp3)-H amination catalyzed by an iminium salt
Chem. Sci., 2018, 9,935-939
DOI: 10.1039/C7SC03968A, Edge Article
DOI: 10.1039/C7SC03968A, Edge Article
Open Access  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Logan A. Combee, Balaram Raya, Daoyong Wang, Michael K. Hilinski
This report details the first organocatalytic method for nitrenoid transfer and its application to intermolecular, site-selective C(sp3)-H amination.
The content of this RSS Feed (c) The Royal Society of Chemistry
This report details the first organocatalytic method for nitrenoid transfer and its application to intermolecular, site-selective C(sp3)-H amination.
The content of this RSS Feed (c) The Royal Society of Chemistry
04 Dec 21:49
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Site-selective bromination of sp3 C-H bonds
Chem. Sci., 2018, 9,100-104
DOI: 10.1039/C7SC04611A, Edge Article
DOI: 10.1039/C7SC04611A, Edge Article
Open Access  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Shyam Sathyamoorthi, Shibdas Banerjee, J. Du Bois, Noah Z. Burns, Richard N. Zare
A method for converting sp3 C-H to C-Br bonds using an N-methyl sulfamate directing group is described. For all sulfamates examined, bromination occurs with high selectivity at the [gamma]-carbon, affording a predictable method for C-H bond halogenation.
The content of this RSS Feed (c) The Royal Society of Chemistry
A method for converting sp3 C-H to C-Br bonds using an N-methyl sulfamate directing group is described. For all sulfamates examined, bromination occurs with high selectivity at the [gamma]-carbon, affording a predictable method for C-H bond halogenation.
The content of this RSS Feed (c) The Royal Society of Chemistry
30 Nov 20:48
Predictive Model for Oxidative C–H Bond Functionalization Reactivity with 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone
by Cristian A. Morales-Rivera, Paul E. Floreancig and Peng Liu
Journal of the American Chemical Society
DOI: 10.1021/jacs.7b08902
zhanglinli, 123rliu likes this
28 Nov 15:36
Electrochemical Cobalt-Catalyzed C–H Oxygenation at Room Temperature
by Nicolas Sauermann, Tjark H. Meyer, Cong Tian and Lutz Ackermann
Journal of the American Chemical Society
DOI: 10.1021/jacs.7b11025
20 Nov 14:01
Selective ortho C–H Activation of Pyridines Directed by Lewis Acidic Boron of PBP Pincer Iridium Complexes
by Wei-Chun Shih and Oleg V. Ozerov
Journal of the American Chemical Society
DOI: 10.1021/jacs.7b10570
adelequeen, senmiao xu and 4 others like this
09 Nov 15:25
Electro-oxidative C(sp3)–H Amination of Azoles via Intermolecular Oxidative C(sp3)–H/N–H Cross-Coupling
by Jiwei Wu, Yi Zhou, Yuchen Zhou, Chien-Wei Chiang and Aiwen Lei
ACS Catalysis
DOI: 10.1021/acscatal.7b03551
大河弯弯的, cyymumumao and 4 others like this
01 Nov 14:17
Cation Radical Accelerated Nucleophilic Aromatic Substitution via Organic Photoredox Catalysis
by Nicholas E. S. Tay and David A. Nicewicz
Journal of the American Chemical Society
DOI: 10.1021/jacs.7b10076
27 Oct 21:27
Oxyfunctionalization of the Remote C−H Bonds of Aliphatic Amines by Decatungstate Photocatalysis
Going with the floW: Decatungstate anion, a UV absorbing photocatalyst, was utilized in the conversion of unprotected aliphatic amines, into products containing a ketone functionality at a remote position, by using either H2O2 or O2 as the terminal oxidant. NMR studies employing LED-irradiated samples aided in the identification of a key reaction intermediate, and ultimately allowed the transformation to be translated into flow.
[Communication]
Danielle M. Schultz, François Lévesque, Daniel A. DiRocco, Mikhail Reibarkh, Yining Ji, Leo A. Joyce, James F. Dropinski, Huaming Sheng, Benjamin D. Sherry, Ian W. Davies
Angew. Chem. Int. Ed., October 26, 2017, https://doi.org/10.1002/anie.201707537 Read article
24 Oct 02:07
Catalytic Methane Monofunctionalization by an Electrogenerated High-Valent Pd Intermediate
by Matthew E. O’Reilly, R. Soyoung Kim, Seokjoon Oh and Yogesh Surendranath
ACS Central Science
DOI: 10.1021/acscentsci.7b00342
27 Sep 15:45
"Kalsoy." Kalsoy island and Kallur lighthouse in sunset light in the Faroe Islands.
(© Copyright Wojciech Kruczynski / 2017 National Geographic Nature Photographer of the Year)
2017 National Geographic Nature Photographer of the Year Contest (15 photos)
National Geographic Magazine has opened its annual photo contest for 2017, with the deadline for submissions coming up on November 17. The Grand Prize Winner will receive $10,000, publication in National Geographic Magazine and a feature on National Geographic’s Instagram account. The folks at National Geographic were, once more, kind enough to let me choose among the contest entries so far for display here. The captions below were written by the individual photographers, and lightly edited for style.
Matthieu DUFOURNEAUD likes this
24 Sep 19:35
Enantioselective Synthesis of Cyclobutenes by Intermolecular [2+2] Cycloaddition with Non-C2 Symmetric Digold Catalysts
by Cristina García-Morales, Beatrice Ranieri, Imma Escofet, Laura López-Suarez, Carla Obradors, Andrey I. Konovalov and Antonio M. Echavarren
Journal of the American Chemical Society
DOI: 10.1021/jacs.7b07651
Naoko Ichiishi, Nuria and 7 others like this
22 Sep 14:24
Meta-Selective C−H Borylation of Benzylamine, Phenethylamine and Phenylpropylamine-Derived Amides Enabled by a Single Anionic Ligand
Clever positioning: A bipyridine ligand incorporating a remote anionic sulfonate group directs iridium-catalyzed borylation to the meta-position on a range of amide-containing arenes. It is proposed that this selectivity is a result of a hydrogen bonding interaction to correctly position the iridium metal centre in the crucial C−H activation.
[Communication]
Holly J. Davis, Georgi R. Genov, Robert J. Phipps
Angew. Chem. Int. Ed., September 19, 2017, https://doi.org/10.1002/anie.201708967 Read article
19 Sep 16:42
[ASAP] Flow Electrolysis Cells for the Synthetic Organic Chemistry Laboratory
by Derek Pletcher, Robert A. Green and Richard C. D. Brown
Chemical Reviews
DOI: 10.1021/acs.chemrev.7b00360