21 Sep 14:09
by Sankaranarayanapillai Shylesh, Amit A. Gokhale, Christopher R. Ho and Alexis T. Bell
Accounts of Chemical Research
DOI: 10.1021/acs.accounts.7b00354
14 Feb 16:35
by Satheesh Borra, D. Chandrasekhar, Susanta Adhikary, Sandeep Rasala, Sabapathi Gokulnath and Ram Awatar Maurya
The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.6b02932
01 Jun 16:11
by Toru Shimizu, Dongyang Huang, Fang Yan, Martin Stranava, Martina Bartosova, Veronika Fojtíková and Markéta Martínková
Chemical Reviews
DOI: 10.1021/acs.chemrev.5b00018
10 Nov 16:23
by Yan Liu, Xiaobing Xi, Chengcheng Ye, Tengfei Gong, Zhiwei Yang, Yong Cui
Abstract
Two chiral carboxylic acid functionalized micro- and mesoporous metal–organic frameworks (MOFs) are constructed by the stepwise assembly of triple-stranded heptametallic helicates with six carboxylic acid groups. The mesoporous MOF with permanent porosity functions as a host for encapsulation of an enantiopure organic amine catalyst by combining carboxylic acids and chiral amines in situ through acid–base interactions. The organocatalyst-loaded framework is shown to be an efficient and recyclable heterogeneous catalyst for the asymmetric direct aldol reactions with significantly enhanced stereoselectivity in relative to the homogeneous organocatalyst.
Two chiral carboxylic acid functionalized micro- and mesoporous metal–organic frameworks (MOFs) are constructed. The mesoporous MOF functions as a host for encapsulation of an enantiopure organic amine by acid–base interactions. The organocatalyst-loaded MOF is an efficient and recyclable heterogeneous catalyst for asymmetric direct aldol reactions, with significantly enhanced stereoselectivity relative to the homogeneous organocatalyst.
