30 Mar 04:00

Ontological Argument

A God who holds the world record for eating the most skateboards is greater than a God who does not hold that record.
30 Mar 19:00

Photo



30 Mar 15:53

Zn-Catalyzed Enantio- and Diastereoselective Formal [4 + 2] Cycloaddition Involving Two Electron-Deficient Partners: Asymmetric Synthesis of Piperidines from 1-Azadienes and Nitro-Alkenes

by John C. K. Chu, Derek M. Dalton and Tomislav Rovis

TOC Graphic

Journal of the American Chemical Society
DOI: 10.1021/jacs.5b00033
30 Mar 14:38

25+ Hilarious Pranks For April Fools’ Day

by Lina D.

Bathroom Is Occupied

Bathroom Is Occupied

Leave A Surprise For Whoever Redoes The Carpet

Leave A Surprise For Whoever Redoes The Carpet

source

Make Dinner For Your Friends

Make Dinner For Your Friends

source

Insect Lamps

Insect Lamps

source

Attach An Airhorn To Their Seat

Attach An Airhorn To Their Seat

source

Make Mentos Ice Bombs For Your Friends That Love Soda

Make Mentos Ice Bombs For Your Friends That Love Soda

source

Fake Poop

Fake Poop

source

Infest Their Office With (fake) Rats

Infest Their Office With (fake) Rats

source

Hang Kim Jong Un On The Staff Picture Wall

Hang  Kim Jong Un  On The Staff Picture Wall

source

Mentos Prank

Mentos Prank

Chicken Soup Shower

Chicken Soup Shower

source

Balloon Prank Fake Out

Balloon Prank Fake Out

source

Plant A Grass Garden In Your Coworker’s Keyboard

Plant A Grass Garden In Your Coworker’s Keyboard

source

Offer Them Some Water In An Original Way

Offer Them Some Water In An Original Way

source

Create An Infinite Loop Of Shopping Carts Around Their Car

Create An Infinite Loop Of Shopping Carts Around Their Car

source

Install An Airhorn As A Door Wall Protector

Install An Airhorn As A Door Wall Protector

source

Paint Soap With Clear Nail Polish And Leave It In The Shower

Paint Soap With Clear Nail Polish And Leave It In The Shower

source

Leave This In Your Roommate’s Bathroom On April Fools’ Day With The Door Shut

Leave This In Your Roommate's Bathroom On April Fools' Day With The Door Shut

source

Replace Air Freshener With Shrimp Scent

Replace Air Freshener With Shrimp Scent

source

Flying Sausages

Flying Sausages

source

Delight Their Taste Buds With Caramel Onions

Delight Their Taste Buds With Caramel Onions

source

The Cage Copier

The Cage Copier

source

Mouse Prank

Mouse Prank

source

Become A Seat And Watch People’s Reactions

Become A Seat And Watch People’s Reactions

source

Turn Their Cubicle Into A Bathroom

Turn Their Cubicle Into A Bathroom

30 Mar 04:20

Nickel-Catalyzed Direct Thiolation of C(sp3)–H Bonds in Aliphatic Amides

by Xie Wang, Renhua Qiu, Chunyang Yan, Vutukuri Prakash Reddy, Longzhi Zhu, Xinhua Xu and Shuang-Feng Yin

TOC Graphic

Organic Letters
DOI: 10.1021/acs.orglett.5b00706
30 Mar 00:27

Photo



31 Mar 00:00

“My friend sent an awkward memo at work today.”  - WindumArc



“My friend sent an awkward memo at work today.”  - WindumArc

30 Mar 15:28

Saturday Morning Breakfast Cereal - Robot Horror

by admin@smbc-comics.com

Hovertext: In Robot romantic comedies, everyone finds their perfect mate with no difficulty. The humor comes from imagining doing that without a digital brain.


New comic!
Today's News:

 Cards Against Humanity Science Packs are funding a scholarship!

30 Mar 14:58

A Black and Blue Life: A Coal Miner Becomes a Photographer of Exquisite Waves and Seascapes

by Christopher Jobson

Convection - Ray Collins

Australian photographer Ray Collins first picked up a camera in 2007 and used it to photograph his friends surfing around his home after long shifts working in a nearby coal mine. His attention quickly shifted from his friends to patterns and forms he noticed in the waves. Collins, who is colorblind, was also drawn to the interplay of light and water, perhaps more attune to contrast than the nuance of color. He poetically refers to this switch from coal miner to fine art photographer as a balance between his “black life and blue life.”

The accolades, awards, and sponsorships have been heaped on Collins leading to the publication of his first book, Found at Sea, he also has a wide variety of prints on his website, and you can follow his photography day-to-day on Instagram. (via Laughing Squid)

Underwater - Ray Collins

Fury - Ray Collins

Ominous - Ray Collins

Beneath The Vortex - Ray Collins

Viscous  - Ray Collins

Ripples - Ray Collins

Rainbow - Ray Collins

ray-11

Sunburst - Ray Collins

31 Mar 14:35

by Left Handed Toons

30 Mar 12:11

Photo



30 Mar 01:42

4gifs: Wake up so I can bite you. [video]



4gifs:

Wake up so I can bite you. [video]

29 Mar 05:02

(photo via repostuje)



(photo via repostuje)

31 Mar 16:41

The Big Picture: Gorgeous shot captures a drone's fiery flight

by Andrew Tarantola
Photographer Calder Wilson added an explosive new method to his long exposure "light paintings" earlier this year when he was struck by a brilliant notion: Strap some leftover New Year's fireworks to the back of a UAV, light them up and then lift off...
31 Mar 12:40

Palladium-Catalyzed C–H Functionalization of Acyldiazomethane and Tandem Cross-Coupling Reactions

by Fei Ye, Shuanglin Qu, Lei Zhou, Cheng Peng, Chengpeng Wang, Jiajia Cheng, Mohammad Lokman Hossain, Yizhou Liu, Yan Zhang, Zhi-Xiang Wang and Jianbo Wang

TOC Graphic

Journal of the American Chemical Society
DOI: 10.1021/ja513275c
31 Mar 06:00

Почему в штате Вермонт (США) взымают специальный налог с безоружных



Есть в США такой штат-мечта — Вермонт. В этом штате не требуется никаких специальных разрешений на огнестрельное оружие и его ношение (скрытое или открытое). При этом, штат Вермонт традиционно занимает первую тройку самых безопасных штатов США. Это штат с одним из самых низких показателей убийств, ограблений, нападений и изнасилований на душу населения.

Итак, представитель штата Вермонт Фред Маслак, как истинный поклонник конституции США и Второй Поправки предложил регистрировать тех, кто не владеет оружием и обязать их платить налог штата в размере 500 долларов.

Таким образом, Вашингтон вводит налог на особый вид роскоши — на роскошное право возлагать свою безопасность на плечи других. И всего за каких-то символических 500 долларов США. Именно такую ​​цену господин Маслак считает логичным за привилегированное право не владеть оружием в штате Вермонт.

Фред Маслак твердо уверен, что Вторая Поправка не только подразумевает право добросовестного гражданина на участие в вооруженном ополчении, но и является прямым его обязанностью, т.к. вооруженные граждане являются прямым противовесом преступности и преступной диктатуре и поскольку монополия силы в правительстве возможна только при разоружения граждан.

Граждане Вермонта должны быть готовы защитить себя и свой штат против любой возникающей угрозы. А те, кто не готов защищать свой штат — должны за это платить.



Согласно закону все взрослые, которые не обладают оружием, должны быть зарегистрированы, так как власть имеет право знать, кто из граждан не готов защищать штат, считает Маслак. И это несмотря на то, что Вермонт и так один из самых вооруженных штатов США и единственный, где не требуется разрешения на скрытое ношение оружия.

Логика законопроекта весьма проста — люди без оружия требуют больше защиты со стороны сил правопорядка. И, соответственно, должны платить больший налог за эту защиту.

источник

31 Mar 04:30

d3dk0w: awwww-cute: I have to use a decoy keyboard to get any...



d3dk0w:

awwww-cute:

I have to use a decoy keyboard to get any work done

relatable

30 Mar 20:13

Palladium(II)-Catalyzed Directed Trifluoromethylthiolation of Unactivated C(sp3)–H Bonds

by Heng-Ying Xiong, Tatiana Besset, Dominique Cahard and Xavier Pannecoucke

TOC Graphic

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00505
30 Mar 17:02

Angular-Shaped 4,9-Dialkylnaphthodithiophene-Based Donor–Acceptor Copolymers for Efficient Polymer Solar Cells and High-Mobility Field-Effect Transistors

by Sheng-Wen Cheng, Che-En Tsai, Wei-Wei Liang, Yung-Lung Chen, Fong-Yi Cao, Chain-Shu Hsu and Yen-Ju Cheng

TOC Graphic

Macromolecules
DOI: 10.1021/acs.macromol.5b00098
30 Mar 14:24

Metal-Free Synthesis of Indole via NIS-Mediated Cascade C–N Bond Formation/Aromatization

by Yin-Long Li, Jian Li, Ai-Lun Ma, Ya-Nan Huang and Jun Deng

TOC Graphic

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.5b00090
30 Mar 13:50

Cyclic Hypervalent Iodine Reagents and Iron Catalysts: The Winning Team for Late-Stage CH Azidation

by Maria Victoria Vita, Jerome Waser
Thumbnail image of graphical abstract

1+1=3: By combining the exceptional reactivities of cyclic hypervalent iodine reagents and iron catalysts, Sharma and Hartwig achieved the azidation of C[BOND]H bonds with unprecedented efficiency and selectivity. The late-stage introduction of azides into complex bioactive molecules will greatly facilitate the synthesis of analogues and accelerate the discovery of new chemical entities.

30 Mar 13:40

A Highly Efficient Gold-Catalyzed Photoredox α-C(sp3)H Alkynylation of Tertiary Aliphatic Amines with Sunlight

by Jin Xie, Shuai Shi, Tuo Zhang, Nina Mehrkens, Matthias Rudolph, A. Stephen K. Hashmi

Abstract

A new α-C(sp3)[BOND]H alkynylation of unactivated tertiary aliphatic amines with 1-iodoalkynes as radical alkynylating reagents in the presence of [Au2(μ-dppm)2]2+ in sunlight provides propargylic amines. Based on mechanistic studies, a C[BOND]C coupling of an α-aminoalkyl radical and an alkynyl radical is proposed for the C(sp3)[BOND]C(sp) bond formation. The mild, convenient, efficient, and highly selective C(sp3)[BOND]H alkynylation reaction shows excellent regioselectivity and good functional-group compatibility. A scale-up to gram quantities is possible with sunlight used as a clean and sustainable energy source.

Thumbnail image of graphical abstract

Golden sunshine: With 1-iodoalkynes as radical alkynylation reagents, unactivated tertiary aliphatic amines react in the presence of [Au2(μ-dppm)2]2+ (dppm=bis(diphenylphosphanyl)methane) in sunlight to afford propargylamines. A C[BOND]C coupling of an α-aminoalkyl radical and an alkynyl radical was proposed as the mechanism.

30 Mar 13:40

Synthesis of Polybenzoquinolines as Precursors for Nitrogen-Doped Graphene Nanoribbons

by David J. Dibble, Young S. Park, Amir Mazaheripour, Mehran J. Umerani, Joseph W. Ziller, Alon A. Gorodetsky

Abstract

Graphene nanoribbons (GNRs) represent promising materials for the next generation of nanoscale electronics. However, despite substantial progress towards the bottom-up synthesis of chemically and structurally well-defined all-carbon GNRs, strategies for the preparation of their nitrogen-doped analogs remain at a nascent stage. This scarce literature precedent is surprising given the established use of substitutional doping for tuning the properties of electronic materials. Herein, we report the synthesis of a previously unknown class of polybenzoquinoline-based materials, which have potential as GNR precursors. Our scalable and facile approach employs few synthetic steps, inexpensive commercial starting materials, and straightforward reaction conditions. Moreover, due to the importance of quinoline derivatives for a variety of applications, the reported findings may hold implications across a diverse range of chemical and physical disciplines.

Thumbnail image of graphical abstract

Towards nitrogen-doped nanoribbons: A previously unknown class of benzoquinoline-based materials was synthesized via the aza-Diels–Alder reaction. The reported straightforward and facile methodology provides ready access to a potentially diverse range of polybenzoquinolines. These materials hold promise as key intermediates for the synthesis of modular nitrogen-doped graphene nanoribbons.

30 Mar 12:24

Design of (X-DADAD)n Type Copolymers for Efficient Bulk Heterojunction Organic Solar Cells

by Alexander V. Akkuratov, Diana K. Susarova, Oleg V. Kozlov, Alexander V. Chernyak, Yuriy L. Moskvin, Lubov A. Frolova, Maxim S. Pshenichnikov and Pavel A. Troshin

TOC Graphic

Macromolecules
DOI: 10.1021/ma5023956
30 Mar 00:41

Photo