22 Mar 13:59

Comic: The Deliberator

by Tycho@penny-arcade.com (Tycho)
New Comic: The Deliberator
22 Mar 16:53

Saturday Morning Breakfast Cereal - Important Moments in Philosophy

by tech@thehiveworks.com


Click here to go see the bonus panel!

Hovertext:
The nice thing about Nietzsche is you don't have to write his dialog for him.

New comic!
Today's News:

We're just about sold out of London BAHFest tickets. Today is the last day I can guarantee any type of ticket, so please buy soon if you're planning to go!

22 Mar 12:24

Comic: The Deliberator

by Tycho@penny-arcade.com (Tycho)
New Comic: The Deliberator
23 Mar 15:38

Bioinspired Asymmetric Synthesis of Hispidanin A

by Fuzhuo Li, Qian Tu, Sijia Chen, Lei Zhu, Yu Lan, Jianxian Gong, Zhen Yang

Abstract

The first enantiospecific synthesis of hispidanin A (4), a dimeric diterpenoid from the rhizomes of Isodon hispida, was achieved with a longest linear sequence of 12 steps in 6.5 % overall yield. A key component is the use of the abundant and naturally occurring diterpenoids (+)-sclareolide and (+)-sclareol as starting materials, which enables the gram-scale preparation of the key intermediates totarane (1) and s-trans-12E,14-labdadien-20,8β-olide (2). Subsequently a thermal or an erbium-catalyzed intermolecular Diels–Alder reaction of totarane (1) with labdadienolide (2) provide convergent and rapid access to the natural product hispidanin A (4). The synthetic studies have offered significant impetus for the efficient construction of these architecturally complex natural products.

Thumbnail image of graphical abstract

When two become one: An enantiospecific synthesis of hispidanin A, a dimeric diterpenoid from Isodon hispida, was achieved with a longest linear sequence of 12 steps and 6.5 % overall yield. Key component are the use of the diterpenoids (+)-sclareolide and (+)-sclareol as starting materials to prepare the key intermediates totarane (1) and labdadienolide (2), and intermolecular Diels–Alder reaction of 1 with 2 to give hispidanin A.

24 Mar 09:23

Fall from grace

by Scandinavia and the World
Fall from grace

Fall from grace

View Comic!




23 Mar 00:03

Sub-4 nm PtZn Intermetallic Nanoparticles for Enhanced Mass and Specific Activities in Catalytic Electrooxidation Reaction

by Zhiyuan Qi, Chaoxian Xiao, Cong Liu, Tian Wei Goh, Lin Zhou, Raghu Maligal-Ganesh, Yuchen Pei, Xinle Li, Larry A. Curtiss and Wenyu Huang

TOC Graphic

Journal of the American Chemical Society
DOI: 10.1021/jacs.6b12780
22 Mar 07:42

Chapter 62: Page 2

Based on a true story.
22 Mar 22:39

Palladium-Catalyzed β-Mesylation of Simple Amide via Primary sp3 C–H Activation

by Ren Zhao and Wenjun Lu

TOC Graphic

Organic Letters
DOI: 10.1021/acs.orglett.7b00536
22 Mar 16:11

What Food Geniuses Eat for Lunch

by Stella Blackmon

What Food Geniuses Eat for Lunch

I worked at a tiny Italian restaurant during college, and every Friday, for four years, the owner would make the same lunch: a lightly-dressed spinach salad, with four grilled shrimp and two tomato slices — as long as the tomato was “bright red and soft, not mushy.” And every Friday, for four years, I was puzzled.… Read more

The post What Food Geniuses Eat for Lunch appeared first on A Cup of Jo.

23 Mar 05:06

Pixely

by David M Willis

Dumbing of Age Vol. 5: Hey, Guess What, I’m a Lesbian!

Dumbing of Age Vol. 5: Hey, Guess What, I'm a Lesbian!
 

Written by: David Willis
Cover by: David Willis
Art by: David Willis
Price: $19.99

Joyce was homeschooled, and these initial few weeks of college have been her first foray into public education. Joyce worries college is changing her, but when her childhood friend Becky shows up at the door, Joyce begins to learn exactly how much. (Also, Dina runs around in an adorable triceratops hoodie.)

Buy now on comiXology!

also i’ve submitted my book 6 kickstarter for review, so that should be starting up soon, get ready

23 Mar 13:17

High-Performance Nonfullerene Polymer Solar Cells based on Imide-Functionalized Wide-Bandgap Polymers

by Baobing Fan, Kai Zhang, Xiao-Fang Jiang, Lei Ying, Fei Huang, Yong Cao

High-performance nonfullerene polymer solar cells (PSCs) are developed by integrating the nonfullerene electron-accepting material 3,9-bis(2-methylene-(3-(1,1-dicyanomethylene)-indanone))-5,5,11,11-tetrakis(4-hexylphenyl)-dithieno[2,3-d:2′,3′-d′]-s-indaceno[1,2-b:5,6-b′]dithiophne) (ITIC) with a wide-bandgap electron-donating polymer PTzBI or PTzBI-DT, which consists of an imide functionalized benzotriazole (TzBI) building block. Detailed investigations reveal that the extension of conjugation can affect the optical and electronic properties, molecular aggregation properties, charge separation in the bulk-heterojunction films, and thus the overall photovoltaic performances. Single-junction PSCs based on PTzBI:ITIC and PTzBI-DT:ITIC exhibit remarkable power conversion efficiencies (PCEs) of 10.24% and 9.43%, respectively. To our knowledge, these PCEs are the highest efficiency values obtained based on electron-donating conjugated polymers consisting of imide-functionalized electron-withdrawing building blocks. Of particular interest is that the resulting device based on PTzBI exhibits remarkable PCE of 7% with the thickness of active layer of 300 nm, which is among the highest values of nonfullerene PSCs utilizing thick photoactive layer. Additionally, the device based on PTzBI:ITIC exhibits prominent stability, for which the PCE remains as 9.34% after thermal annealing at 130 °C for 120 min. These findings demonstrate the great promise of using this series of wide-bandgap conjugated polymers as electron-donating materials for high-performance nonfullerene solar cells toward high-throughput roll-to-roll processing technology.

Thumbnail image of graphical abstract

High-performance nonfullerene polymer solar cells with power conversion efficiencies of around 10% are achieved by integrating the wide-bandgap polymers PTzBI or PTzBI-DT with a nonfullerene acceptor ITIC. The extension of conjugation can affect the optical and electronic properties, molecular aggregation properties, and charge separation in the bulk-heterojunction films, and thus the overall photovoltaic performances.

24 Mar 04:58

Girl Genius for Friday, March 24, 2017

The Girl Genius comic for Friday, March 24, 2017 has been posted.
22 Mar 18:08

Saturday Morning Breakfast Cereal - Important Moments in Philosophy

by tech@thehiveworks.com


Click here to go see the bonus panel!

Hovertext:
The nice thing about Nietzsche is you don't have to write his dialog for him.

New comic!
Today's News:

We're just about sold out of London BAHFest tickets. Today is the last day I can guarantee any type of ticket, so please buy soon if you're planning to go!

24 Mar 05:02

Comic for 2017.03.24

New Cyanide and Happiness Comic
24 Mar 07:12

Comic: Hell’s Kitchen

by Tycho@penny-arcade.com (Tycho)
New Comic: Hell’s Kitchen
23 Mar 01:29

Nanoengineering of Core–Shell Magnetic Mesoporous Microspheres with Tunable Surface Roughness

by Qin Yue, Yu Zhang, Yongjian Jiang, Jialuo Li, Hongwei Zhang, Chengzhong Yu, Ahmed A. Elzatahry, Abdulaziz Alghamdi, Yonghui Deng and Dongyuan Zhao

TOC Graphic

Journal of the American Chemical Society
DOI: 10.1021/jacs.7b01464
24 Mar 02:53

Nickel-Catalyzed Aminoxylation of Inert Aliphatic C(sp3)–H Bonds with Stable Nitroxyl Radicals under Air: One-Pot Route to α-Formyl Acid Derivatives

by Chunxia Wang, Luoqiang Zhang and Jingsong You

TOC Graphic

Organic Letters
DOI: 10.1021/acs.orglett.7b00479
24 Mar 04:14

Smidge

by David M Willis
22 Mar 22:07

The First Thing You Should Say When Calling 911 on a Mobile Phone

by Patrick Allan

In the frenzy of a real emergency, it can be hard to think straight. Yes, it’s important to give your name and explain the situation when you call 911, but there’s some things you should tell them first if you’re calling from a mobile phone, just in case.

Read more...

24 Mar 13:57

Flag

There's a compromise bill to keep the notification bar but at least charge the battery.
23 Mar 05:05

Comic for March 23, 2017

Dilbert readers - Please visit Dilbert.com to read this feature. Due to changes with our feeds, we are now making this RSS feed a link to Dilbert.com.
23 Mar 11:06

How to Stop Destroying Your Clothes in the Wash

by Kristin Wong

Theoretically, it’s better to spend more on quality, but that’s only true if the quality item lasts. I used to have a bad habit of tossing my clothes from the hamper to the dryer without giving it much thought. If you buy quality, this is an expensive mistake. Here’s how to take better care of your clothes.

Read more...

23 Mar 15:16

Saturday Morning Breakfast Cereal - Unintended Consequences

by tech@thehiveworks.com


Click here to go see the bonus panel!

Hovertext:
Four-hundred years from now, I will be hailed as a prophet.

New comic!
Today's News:

Hey geeks! London tickets are pretty close to sold out, but we moved over some of our reserved spots. So, there's still a little availability!

24 Mar 05:04

Comic for March 24, 2017

Dilbert readers - Please visit Dilbert.com to read this feature. Due to changes with our feeds, we are now making this RSS feed a link to Dilbert.com.
24 Mar 08:26

Comic: Hell’s Kitchen

by Tycho@penny-arcade.com (Tycho)
New Comic: Hell’s Kitchen