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26 Nov 05:16

A nickel-mediated oxidative [small alpha]-C(sp3)-H functionalization of amides with allylic alcohols terminated by radical 1,2-aryl migration

Chem. Commun., 2015, 51,749-752
DOI: 10.1039/C4CC08797F, Communication
Ren-Jie Song, Yong-Qiang Tu, Dao-Yong Zhu, Fu-Min Zhang, Shao-Hua Wang
A Ni-mediated oxidative C(sp3)-H functionalization of N,N-substituted amides with [small alpha],[small alpha]-diaryl allylic alcohols through a radical 1,2-aryl migration process has been developed. This process features a broad substrate scope and excellent functional group tolerance.
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