Analytical Chemistry
DOI: 10.1021/acs.analchem.2c03378
Pre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic niche
Pre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic niche, Published online: 06 November 2017; doi:10.1038/s41467-017-01433-3
NatureArticleSnippet(type=short-summary, markup=Exosomes are extracellular vesicles that can favor tumor development and metastasis. Here, the authors show that cancer exosomes may also exert a suppressive function; in fact, exosomes from non-metastatic melanoma cells can lead to the recruitment of patrolling monocytes, which clear cancer cells at the pre-metastatic niche.
, isJats=true)Nature Materials 15, 775 (2016). doi:10.1038/nmat4600
Authors: Mark C. Weidman, Detlef-M. Smilgies & William A. Tisdale