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13 Jan 01:56

[ASAP] Non-Invasive, Reliable, and Fast Quantification of DNA Loading on Gold Nanoparticles by a One-Step Optical Measurement

by Jaewon Lee and Seungwoo Lee

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Analytical Chemistry
DOI: 10.1021/acs.analchem.2c03378
10 May 12:46

[ASAP] Probing Graphene Interfacial Reactivity via Simultaneous and Colocalized Raman–Scanning Electrochemical Microscopy Imaging and Interrogation

by Noah B. Schorr, Annie G. Jiang, Joaquín Rodríguez-López

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Analytical Chemistry
DOI: 10.1021/acs.analchem.8b00730
17 Apr 14:17

Interactions of Fullerene‐Polyglycerol Sulfates at Viral and Cellular Interfaces

Small, EarlyView.
18 Nov 12:23

Mechanism of RNA polymerase II stalling by DNA alkylation [Biochemistry]

by Stefano Malvezzi, Lucas Farnung, Claudia M. N. Aloisi, Todor Angelov, Patrick Cramer, Shana J. Sturla
Several anticancer agents that form DNA adducts in the minor groove interfere with DNA replication and transcription to induce apoptosis. Therapeutic resistance can occur, however, when cells are proficient in the removal of drug-induced damage. Acylfulvenes are a class of experimental anticancer agents with a unique repair profile suggesting their...
06 Nov 13:56

Pre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic niche

by Michael P. Plebanek

Pre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic niche

Pre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic niche, Published online: 06 November 2017; doi:10.1038/s41467-017-01433-3

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Exosomes are extracellular vesicles that can favor tumor development and metastasis. Here, the authors show that cancer exosomes may also exert a suppressive function; in fact, exosomes from non-metastatic melanoma cells can lead to the recruitment of patrolling monocytes, which clear cancer cells at the pre-metastatic niche.

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26 Aug 15:14

Flexible SiC/Si3N4 Composite Nanofibers with in Situ Embedded Graphite for Highly Efficient Electromagnetic Wave Absorption

by Peng Wang, Laifei Cheng, Yani Zhang and Litong Zhang

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ACS Applied Materials & Interfaces
DOI: 10.1021/acsami.7b05382
12 Aug 08:46

Comparison of Methods to Release Mucin-Type O-Glycans for Glycomic Analysis

by Yukinobu Goso, Tsukiko Sugaya, Kazuhiko Ishihara and Makoto Kurihara

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Analytical Chemistry
DOI: 10.1021/acs.analchem.7b01346
02 May 13:41

NGF-TrkA signaling in sensory nerves is required for skeletal adaptation to mechanical loads in mice [Medical Sciences]

by Ryan E. Tomlinson, Zhi Li, Zhu Li, Liliana Minichiello, Ryan C. Riddle, Arun Venkatesan, Thomas L. Clemens
Sensory nerves emanating from the dorsal root extensively innervate the surfaces of mammalian bone, a privileged location for the regulation of biomechanical signaling. Here, we show that NGF-TrkA signaling in skeletal sensory nerves is an early response to mechanical loading of bone and is required to achieve maximal load-induced bone...
29 Mar 09:19

Catalytic Synthesis of N-Heterocycles via Direct C(sp3)–H Amination Using an Air-Stable Iron(III) Species with a Redox-Active Ligand

by Bidraha Bagh, Daniël L. J. Broere, Vivek Sinha, Petrus F. Kuijpers, Nicolaas P. van Leest, Bas de Bruin, Serhiy Demeshko, Maxime A. Siegler and Jarl Ivar van der Vlugt

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Journal of the American Chemical Society
DOI: 10.1021/jacs.7b00270
30 Jun 15:39

Kinetics of the self-assembly of nanocrystal superlattices measured by real-time in situ X-ray scattering

by Mark C. Weidman

Nature Materials 15, 775 (2016). doi:10.1038/nmat4600

Authors: Mark C. Weidman, Detlef-M. Smilgies & William A. Tisdale

08 Jun 18:16

Metallacarboranes as tunable redox potential electrochemical indicators for screening of gene mutation

Chem. Sci., 2016, 7,5786-5797
DOI: 10.1039/C6SC01567K, Edge Article
Open Access Open Access
Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Tania Garcia-Mendiola, Victoria Bayon-Pizarro, Adnana Zaulet, Isabel Fuentes, Felix Pariente, Francesc Teixidor, Clara Vinas, Encarnacion Lorenzo
The electrochemical behaviour of metallocarborane sodium salts and their interactions with DNA have been studied. They are shown to be selective redox indicators with wide-ranging potential as electrochemical indicators in DNA biosensors.
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