Nature Communications, Published online: 20 September 2019; doi:10.1038/s41467-019-12339-7
DNA methylation plays an important role in regulating a wide variety of cellular processes and is implicated in a range of diseases. Here the authors present Casilio-ME to assemble protein complexes to demethylate target loci.yanyu____
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22 Sep 08:26
Enhanced CRISPR-based DNA demethylation by Casilio-ME-mediated RNA-guided coupling of methylcytosine oxidation and DNA repair pathways
by Aziz Taghbalout
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