George M Ongwae

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15 Jan 13:00

[ASAP] Evolution of Cereblon-Mediated Protein Degradation as a Therapeutic Modality

by Philip P. Chamberlain, Laura A. D’Agostino, J. Michael Ellis, Joshua D. Hansen, Mary E. Matyskiela, Joseph J. McDonald, Jennifer R. Riggs, and Lawrence G. Hamann*

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ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.9b00425
15 Jan 12:55

[ASAP] Online Concentration of Bacteria from Tens of Microliter Sample Volumes in Roughened Fused Silica Capillary with Subsequent Analysis by Capillary Electrophoresis and Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry

by Marie Horka´*†, Jir?i´ S?alplachta†, Pavel Kara´sek†, Filip Ru?z?ic?ka‡, and Michal Roth†

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ACS Infectious Diseases
DOI: 10.1021/acsinfecdis.9b00200
02 Apr 07:58

[ASAP] De Novo Designed Amphipathic a-Helical Antimicrobial Peptides Incorporating Dab and Dap Residues on the Polar Face To Treat the Gram-Negative Pathogen, Acinetobacter baumannii

by Colin T. Mant, Ziqing Jiang, Lajos Gera, Tim Davis, Kirsten L. Nelson, Shaun Bevers, Robert S. Hodges

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Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.8b01785
02 Apr 07:58

[ASAP] Correction to 6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors

by Patrick Sarver, Michael Acker, Jeffrey T. Bagdanoff, Zhouliang Chen, Ying-Nan Chen, Homan Chan, Brant Firestone, Michelle Fodor, Jorge Fortanet, Huaixiang Hao, Murphy Hentemann, Andriana Jouk, Mitsunori Kato, Robert Koenig, Laura R. LaBonte, Gang Liu, Shumei Liu, Chen Liu, Eric McNeill, Morvarid Mohseni, Michael D. Shultz, Martin Sendzik, Travis Stams, Stan Spence, Victoriano Tamez, Ritesh Tichkule, Christopher Towler, Hongyun Wang, Ping Wang, Sarah L. Williams, Bing Yu, Matthew J. LaMarche
Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b00436