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30 Nov 22:02

Bioorthogonal prodrug activation driven by a strain-promoted 1,3-dipolar cycloaddition

Chem. Sci., 2015, 6,1212-1218
DOI: 10.1039/C4SC02574A, Edge Article
Open Access Open Access
Siddharth S. Matikonda, Douglas L. Orsi, Verena Staudacher, Imogen A. Jenkins, Franziska Fiedler, Jiayi Chen, Allan B. Gamble
Bioorthogonal prodrug activation controlled by the reaction of a trans-cyclooctene with an azide-functionalized prodrug is presented.
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