Shared posts

08 Oct 11:03

yui-and-hinata: thespywhospies: l3ertholdtfubar: i really don’t get the whole “but how will we...

yui-and-hinata:

thespywhospies:

l3ertholdtfubar:

i really don’t get the whole “but how will we explain it to my kids" claim about like public nursing or gay couples

little kids are nearly blank slates they will accept pretty much anything you tell them and go with it.

unless it’s quantum physics. please do not talk to your 4-year-old about that.

yes they might get shot by will smith

image

I feel like we never really hear from the MIB fandom, it’s good to see you

You might hear from them more often than you think.

08 Oct 11:03

sithlordette: I love drinking pomegranate green tea from a semi-transparent mug while...

sithlordette:

I love drinking pomegranate green tea from a semi-transparent mug while teaching because it’s yummy and has antioxidants but it also looks like I’m drinking blood and it never hurts for your students to fear you.

08 Oct 11:00

Perfect Disguise

08 Oct 10:45

Don't let fear of bioweapons kill off science

Overzealous suppression of disease research because of a fear of bioweapons makes the world less safe, not more, says Debora MacKenzie
    






08 Oct 10:35

This is how to taking picture when stone age

08 Oct 10:33

Making lightbulbs.

08 Oct 10:31

Ninja bunny

08 Oct 10:18

I bet we would plant if they did these…

08 Oct 10:10

That is a freaking awesome fire pit screen

08 Oct 10:10

Scumbag Prince

08 Oct 10:04

Biology: Multiplication and Division

08 Oct 08:50

Angry cat is angry

08 Oct 08:49

Three types of rock.

08 Oct 08:43

norsevikingqueen: www.thevikingqueen.com

07 Oct 08:25

My brother's Halloween costume...

07 Oct 08:22

Photo











07 Oct 08:20

altern-pinup: Alternative pinup girls http://bit.ly/1awcnsl



altern-pinup:

Alternative pinup girls http://bit.ly/1awcnsl

07 Oct 08:19

geekgirlsmash: lulz-time: tayboox0x0: There’s a point in a...













geekgirlsmash:

lulz-time:

tayboox0x0:

There’s a point in a prank where u just say that’s too much

I don’t feel that I need to explain my art to you, Warren.

07 Oct 08:17

Awesome Lady Venom Full Body Paint

07 Oct 08:16

I thought being in love was supposed to make you happy

07 Oct 08:16

How I feel after last night

07 Oct 08:12

Ping pong balls + Liquid Nitrogen

07 Oct 08:08

My life in a nutshell

07 Oct 08:08

Not today live

07 Oct 08:06

Look, you call it a PS3, but about 85% of the time, it’s just my Netflix-and-Bioware machine.

Look, you call it a PS3, but about 85% of the time, it’s just my Netflix-and-Bioware machine.

07 Oct 08:04

It took them long enough!

07 Oct 08:04

Really know what's important in life

04 Oct 11:50

An easy guide to infinite chocolate

04 Oct 11:44

Scientific Paradoxes are Omens of Advance [Starts With A Bang]

by Ethan

“Ignorance more frequently begets confidence than does knowledge: it is those who know little, and not those who know much, who so positively assert that this or that problem will never be solved by science.” -Charles Darwin

There are problems with science today, no doubt. With all the knowledge we’ve accumulated about the Universe, from the smallest subatomic scales to the farthest recesses of deep space, there are still realms and regimes where our best theories fail, where the predictions and the data don’t match, and where no known explanation is sufficient for the phenomena that shows up.

Image credit: The Michelson-Morley interferometer, via University of Virginia.

Image credit: The Michelson-Morley interferometer, via University of Virginia.

But this is where all the potential for scientific growth lives. Believe it or not, one of the most important scientific paradoxes for astrophysics, cosmology, and the Universe happened… in the wake of Charles Darwin! That’s right, after On the Origin of Species, a crisis came about for physical science.

Image credit: The Open University (UK).

Image credit: The Open University (UK).

You see, Darwin’s idea — that the diversity of life on Earth was explained by the evolution and natural selection of organisms over huge amounts of time — meant that, if Earth’s life had a universal common ancestor, timescale of at least many hundreds of millions of years were required. And with the modern knowledge of geology at the time (in the later half of the 19th Century), which argued for an age of the Earth that was at least a couple of billion years old, we faced a conundrum.

All because of this guy.

Image credit: NASA, via http://solarsystem.nasa.gov/.

Image credit: NASA, via http://solarsystem.nasa.gov/.

You see, if life-as-we-know-it has been around for hundreds of millions of years, that means that the Sun had to have been shining for hundreds of millions of years, too! And that’s not such an easy thing to imagine, since the Sun is the most powerful thing in all of human (and Earth-life) experience. Putting out a continuous 4 × 1026 Watts of power, it’s needless to say that adds up to a lot of energy over hundreds of millions of years!

But energy needs to have a source, and if you want to emit 4 × 1026 Watts for at least hundreds of millions of years, you’d better have an energy source that makes it physically possible.

Image credit: Photograph of William Thomson, Lord Kelvin; photographer unknown.

Image credit: Photograph of William Thomson, Lord Kelvin; photographer unknown.

This was one of the problems that (arguably) the greatest physicist of the day — Lord Kelvin — decided to take on. There was some suspicion that the Sun was made out of many of the same elements that the Earth was (due to the solar spectrum), including a very strong hydrogen signature. Based on that, Kelvin came up with three possible energy sources for the Sun:

  1. The Sun is burning some type of fuel, like hydrogen.
  2. The Sun is feeding off of comets, asteroids, etc., and burns the fuel from them for energy.
  3. The Sun — being incredibly massive — gets its energy from the incredible force of gravity.

And since those were the only three possibilities he could think of, he went and calculated how long the Sun could burn for — emitting a continuous 4 × 1026 Watts of power — before it ran out of energy.

Image credit: user charleytown55il of http://laserpointerforums.com/.

Image credit: user charleytown55il of http://laserpointerforums.com/.

Here on Earth, hydrogen combusting (i.e., burning by combining with oxygen) has the potential to release a tremendous amount of energy. And the Sun is… well, it’s kind of huge, with a total mass of around 2 × 1030 kg in there. If the Sun were made entirely out of hydrogen that was combusting at a rate so that it emitted the right amount of power, how long could it live?

The answer Kelvin came up with was a few tens-of-thousands of years. A long time, for certain, but not nearly long enough. So that ruled out the first option.

Image credit: Gabriel Brammer at Paranal Observatory.

Image credit: Gabriel Brammer at Paranal Observatory.

But what if comets, asteroids, and other transient bodies in our Solar System occasionally refueled our Sun? Could that enable it to burn for long enough, extending its lifetime to the hundreds of millions of years necessary to meet Darwin’s requirements?

If only. Unfortunately, this was even easier to rule out; the amount of mass that would have been added to the Sun, over time, would have wrecked the orbits of the planets, in clear conflict with the laws of gravity. (And yes, even though General Relativity later succeeded Newton’s theory, the argument is still valid.) So that option was out. And that leaves Kelvin’s final consideration.

Image credit: NASA, ESA; created by: G. Bacon (STScI).

Image credit: NASA, ESA; created by: G. Bacon (STScI).

Gravity. Specifically, gravitational contraction, where the gravitational potential energy gets converted into light and heat. Just as, if you drop an object from a great height on Earth, it picks up speed (and hence, kinetic energy), a cloud of contracting gas (or plasma, or anything under its own gravity) will gain some type of energy to compensate for the new, lower-energy gravitational configuration. Kelvin was no doubt the world’s foremost expert on this, as the mechanism by which this happens bears his name: the Kelvin-Helmholtz Mechanism.

The Sun, if it had contracted all of that mass down to its present size in such a way that it emitted energy at the observed rate (4 × 1026 Watts), couldn’t have lived for hundreds of millions of years, but could have lived for about eighteen million years.

Image credit: Copyright 2001-2013, Michael McDarby.

Image credit: Copyright 2001-2013, Michael McDarby.

So that was a problem: Darwin needed hundreds of millions of years to explain biology, geologists needed billions of years to explain the Earth, and Kelvin placed an upper limit of only tens of millions of years on the age of the Sun.

But this seeming paradox was actually an omen of advance; Kelvin had no way of knowing that there was an entirely new type of fuel, that of nuclear fusion!

Image credit: Artwork by Randy Russell.

Image credit: Artwork by Randy Russell.

This would prove to be the way forward, and the resolution to the paradox presented by Kelvin and Darwin’s irreconcilable findings, something unknowable to both men at the time.

Interestingly enough, some stars — white dwarfs in particular – do operate under the Kelvin-Helmholtz Mechanism, and because of their much lower luminosity (intrinsic brightness) than Sun-like stars, will shine for many trillions (or even quadrillions) of years before going dark!

Images credit: HST, NASA and H. Richer (UBC) (R);  NOAO / AURA / NSF (L).

Images credit: HST, NASA and H. Richer (UBC) (R); NOAO / AURA / NSF (L).

We have a significant number of important paradoxes today that are difficult to reconcile, including the black hole firewall problem, the inability to marry quantum mechanics to general relativity, the puzzles of dark matter and dark energy, the strong CP problem, the puzzle of tiny but non-zero neutrino masses, and the hierarchy problem, to name just a few.

These are the edges of knowledge and understanding, and rather than marking the breakdown of science, these are actually beacons that point the way forward. And hopefully, just like you, I can’t wait to find out what’s next!

04 Oct 11:06

Centipede venom blocks pain more effectively than morphine [Life Lines]

by Dr. Dolittle

 

800px-Scolopendra_subspinipes_mutilans_2

Image of a Chinese red-headed centipede from Wikimedia Commons.

Researchers from the Chinese Academy of Sciences and The University of Queensland have discovered a venom from centipedes capable of blocking pain more effectively than morphine!

According to the study authors, centipedes have appeared in the fossil records as far back as 430 million years. They are also one of the first land-dwelling creatures to use venom to incapacitate their prey as shown in the image above of a Chinese red-headed centipede (Scolopendra subspinipes mutilansis) snacking on a roach. The venom is secreted from a pore in the tip of their first set of legs that evolved into claws (forcipules).

Certain voltage-gated sodium channels (Nav1.7) are involved in the sensation of pain. In fact, people with mutated Nav1.7 channels are insensitive to pain.  In a new study published in the Proceedings of the National Academy of Sciences, USA this week, researchers purified a component of the venom that can specifically inhibit Nav1.7 sodium channels.  In the article, they describe it as “a highly selective inhibitor of Nav1.7 that is a more effective analgesic than morphine in rodent pain models.” Prior inhibitors of Nav1.7 channels have been less specific resulting in undesirable side effects. The good news about this new peptide is that it is more specific and according to the results of this study had no negative side effects on blood pressure, heart rate or motor function.

As exciting as these findings are, more studies will be required to determine the safety and efficacy of this new peptide in the treatment of pain in humans.

Source:

Yang S, Xiao Y, Kang D, Liu J, Li Y, Undheim EAB, Klint JK, Rong M, Lai R, King GF.Discovery of a selective NaV1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models. Proceedings of the National Academy of Sciences, USA. Sept. 30, 2013. doi:10.1073/pnas.1306285110