Shared posts

13 Aug 20:38

Protein–peptide docking with a rational and accurate diffusion generative model

by Huifeng Zhao

Nature Machine Intelligence, Published online: 04 August 2025; doi:10.1038/s42256-025-01077-9

Zhao et al. present RAPiDock, an all-atom diffusion model that predicts peptide–protein binding patterns across 92 amino acid types, enabling high-throughput virtual screening for advancing therapeutic peptide design.
28 Jul 20:55

Oral delivery of liquid mRNA therapeutics by an engineered capsule for treatment of preclinical intestinal disease | Science Translational Medicine

RNACap can orally deliver liquid mRNA therapeutics to the intestines in response to intestinal pH, the resulting pressure release, and contractions.
06 Feb 01:53

Bioinspired Supramolecular Lubricating Hydrogel Induced by Shear Force

by Xuewei Zhang, Jian Wang, Hui Jin, Shutao Wang and Wenlong Song

TOC Graphic

Journal of the American Chemical Society
DOI: 10.1021/jacs.7b12886