Control of primary metabolism by a virulence regulatory network promotes robustness in a plant pathogen
Control of primary metabolism by a virulence regulatory network promotes robustness in a plant pathogen, Published online: 29 January 2018; doi:10.1038/s41467-017-02660-4
How pathogens maintain phenotypic robustness during infection is poorly understood. Here the authors couple the virulence regulatory network (VRN) of the pathogen R. solanacearum to a model of its metabolic network, and find that the VRN activates functionally redundant primary metabolism genes to promote phenotypic robustness during infection.