Nature Communications, Published online: 03 November 2025; doi:10.1038/s41467-025-65219-8
Standard monitoring of patients on surgical wards can lead to delays in recognition of changes in health status and subsequent risk. Here, the authors develop and validate a multi-modal machine learning-based framework using vitals monitored continuously with wearables to predict clinical inpatient deterioration alerts.Shared posts
04 Nov 08:22
Development and validation of a clinical wearable deep learning based continuous inhospital deterioration prediction model
by Michael R. Scheid
Zion likes this
04 Nov 08:21
De novo design and evolution of an artificial metathase for cytoplasmic olefin metathesis
by Zhi Zou
Nature Catalysis, Published online: 03 November 2025; doi:10.1038/s41929-025-01436-0
The creation of artificial metalloenzymes compatible with complex biological settings could enable broad applications. Now a de novo-designed artificial metalloenzyme containing an abiological ruthenium cofactor is reported and optimized for ring-closing metathesis in the cytoplasm of whole cells.
23 Feb 08:07
[ASAP] Pillar[6]arene: Light Cleaves Macrocycle to Linear Oligomer Biradical to Initiate Photopolymerization
by Shuai Zhao, Tanlong Xue, Di Pei, Qiuyan Song, Zhichao Pei, Jun Nie, and Yincheng Chang
Organic Letters
DOI: 10.1021/acs.orglett.1c00131
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