Author(s): Aidan J. Lee, Adam S. Ahmed, Brendan A. McCullian, Side Guo, Menglin Zhu, Sisheng Yu, Patrick M. Woodward, Jinwoo Hwang, P. Chris Hammel, and Fengyuan Yang
A systematic study of a ferrimagnetic insulator in a bilayer structure with a succession of nonmagnetic metals opens a possibility of tuning magnetic anisotropy, and also highlights a clear distinction between transition metals and non-transition metals.
[Phys. Rev. Lett. 124, 257202] Published Tue Jun 23, 2020
Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase
Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase, Published online: 13 December 2017; doi:10.1038/s41467-017-02313-6
The Bcr-Abl tyrosine kinases p210 and p190 are linked to different leukemias and differ by the Dbl homology (DH) and Pleckstrin-homology (PH) domains. Here the authors characterize structures of the Bcr-Abl p210 DH and PH domains and find that the PH domain is important for the cellular localization and signaling network of p210.