Sun Bowen

Corrigendum: Cerebral cavernous malformations arise from endothelial gain of MEKK3–KLF2/4 signalling

Nature 536, 7617 (2016). doi:10.1038/nature18311

Authors: Zinan Zhou, Alan T. Tang, Weng-Yew Wong, Sharika Bamezai, Lauren M. Goddard, Robert Shenkar, Su Zhou, Jisheng Yang, Alexander C. Wright, Matthew Foley, J. Simon C. Arthur, Kevin J. Whitehead, Issam A. Awad, Dean Y. Li, Xiangjian Zheng & Mark L. Kahn

Nature532, 122–126 (2016); doi:10.1038/nature17178In this Letter we omitted to cite a relevant paper showing that loss of cerebral cavernous malformation (CCM) signalling confers an increase in KLF2 expression in endothelial cells and in the developing

Climate change and the permafrost carbon feedback

Nature 520, 7546 (2015). doi:10.1038/nature14338

Authors: E. A. G. Schuur, A. D. McGuire, C. Schädel, G. Grosse, J. W. Harden, D. J. Hayes, G. Hugelius, C. D. Koven, P. Kuhry, D. M. Lawrence, S. M. Natali, D. Olefeldt, V. E. Romanovsky, K. Schaefer, M. R. Turetsky, C. C. Treat & J. E. Vonk

Large quantities of organic carbon are stored in frozen soils (permafrost) within Arctic and sub-Arctic regions. A warming climate can induce environmental changes that accelerate the microbial breakdown of organic carbon and the release of the greenhouse gases carbon dioxide and methane. This feedback can accelerate climate change, but the magnitude and timing of greenhouse gas emission from these regions and their impact on climate change remain uncertain. Here we find that current evidence suggests a gradual and prolonged release of greenhouse gas emissions in a warming climate and present a research strategy with which to target poorly understood aspects of permafrost carbon dynamics.