李云梅

Multifunctional nanoparticles have attracted significant interest as biomedical vehicles, combining diagnostic, imaging, and therapeutic properties. We describe herein the construction of new nanoparticle conjugates comprising WS₂ nanorods (NRs) coupled to fluorescent carbon dots (C-dots). We show that the WS₂-C-dot hybrids integrate the unique physical properties of the two species, specifically the photothermal activity of the WS₂ NRs upon irradiation with near-infrared (NIR) light and the excitation-dependent luminescence emission of the C-dots. The WS₂-C-dot NRs have been shown to be non-cytotoxic and have been successfully employed for multicolour cell imaging and targeted cell killing under NIR irradiation, pointing to their potential utilization as effective therapeutic vehicles.

Hybrid nanorods: New composite WS₂-carbon-dot nanorods have been designed and synthesized. Their potential applications for cell imaging and photothermal therapy have been demonstrated (see figure).