Lu_Chen

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11 Oct 03:59

[ASAP] Discovery of dCDK9-202 as a Highly Potent and Selective PROTAC CDK9 Degrader with Strong In Vivo Antitumor Activity

by Lin Ma, Long Xie, Yue Wang, Xian Guan, Ying Zhang, Hanjun Guo, Jiawei Zhou, Jiyang Liu, Xingze Huang, Chunyu He, Ye Chen, Liang Xu, and Xin Han

TOC Graphic

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.5c01111
30 May 00:49

[ASAP] Design of Paromomycin and Neomycin as Sulfated and Hydrophobic Glycans to Target Heparanase-Driven Tumor Progression and Metastasis

by Hawau Abdulsalam, Livia Philip, Kartikey Singh, Malik Farhoud, Neta Ilan, Israel Vlodavsky, and Hien M. Nguyen

TOC Graphic

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.5c00937