21 Oct 14:00

People Shared the Good, the Bad and the Weird Experiences of Mail Order Spouses

20 Oct 15:05

The first 'Red Dead Redemption 2' trailer is here

by David Lumb
Red Dead Redemption hit the last generation of console games with studio Rockstar's signature flair, taking Grand Theft Auto's sandbox gameplay and spreading it across the boundless beauty and brutality of the American Wild West. Two days ago, a teas...
21 Oct 17:00

Monkey tries to teach human how to open a nut

by Mark Frauenfelder


Dangit human. put some muscle in it

This little monkey is trying her hardest to train a limp-limbed human how to crack open a nut with a rock. When she realizes the human isn't making much of an effort, she looks up with an expression that says, "Wtf‽ Help me out here, hairless ape covered in fibers!"

Similarly: Monkey teaches human how to crush leaves

20 Oct 13:06

Cooperative Catalysis and Activation with N-Heterocyclic Carbenes

by Michael H. Wang, Karl A. Scheidt


N-Heterocyclic carbene (NHC) catalysis has emerged as a powerful stratagem in organic synthesis to construct complex molecules primarily by polarity reversal (umpolung) approaches. These unique Lewis bases have been used to generate acyl anions, enolates, and homoenolates in catalytic fashion. Recently, a new strategy has emerged that dramatically expands the synthetic utility of carbene catalysis by leveraging additional activation modes: cooperative catalysis. The careful selection and balance of cocatalysts have led to enhanced reactivity, increased yields, and improved stereoselectivity. In certain cases, these catalytic additives have changed the regioselectivity or diastereoselectivity. This Minireview highlights new advances in NHC cooperative catalysis and surveys the evolution of this field.

Thumbnail image of graphical abstract

N-Heterocyclic carbene (NHC) catalysis is a versatile and powerful strategy to construct complex molecules. To extend and enhance the reactivity of these nucleophiles, cooperative catalysis and related activation approaches have been developed by integrating complementary modes (Lewis/Brønsted acidity, transition-metal processes, photoredox). Recent contributions are summarized in this Minireview.

21 Oct 17:30

'Most Serious' Linux Privilege-Escalation Bug Ever Is Under Active Exploit

by msmash
Reader operator_error shares an ArsTechnica report: A serious vulnerability that has been present for nine years in virtually all versions of the Linux operating system is under active exploit, according to researchers who are advising users to install a patch as soon as possible. While CVE-2016-5195, as the bug is cataloged, amounts to a mere privilege-escalation vulnerability rather than a more serious code-execution vulnerability, there are several reasons many researchers are taking it extremely seriously. For one thing, it's not hard to develop exploits that work reliably. For another, the flaw is located in a section of the Linux kernel that's a part of virtually every distribution of the open-source OS released for almost a decade. What's more, researchers have discovered attack code that indicates the vulnerability is being actively and maliciously exploited in the wild. "It's probably the most serious Linux local privilege escalation ever," Dan Rosenberg, a senior researcher at Azimuth Security, told Ars. "The nature of the vulnerability lends itself to extremely reliable exploitation. This vulnerability has been present for nine years, which is an extremely long period of time." The underlying bug was patched this week by the maintainers of the official Linux kernel. Downstream distributors are in the process of releasing updates that incorporate the fix. Red Hat has classified the vulnerability as "important."

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21 Oct 07:00

Comic: 2016-10-21

New Comic: 2016-10-21
20 Oct 08:55

SSSS page 622

Page 622 is up!
20 Oct 05:00

Menage a 3 - Cooking all night

Menage a 3 - Cooking all night
20 Oct 11:10

Metal–Organic Polyhedron Capped with Cucurbit[8]uril Delivers Doxorubicin to Cancer Cells

by Soumen K. Samanta, Damien Moncelet, Volker Briken and Lyle Isaacs

TOC Graphic

Journal of the American Chemical Society
DOI: 10.1021/jacs.6b09504
20 Oct 20:05

Watch a Japanese Hand Plane Shave Wood Impossibly Thin

by Casey Chan on Sploid, shared by Adam Clark Estes to Gizmodo
Watch a Japanese Hand Plane Shave Wood Impossibly Thin

Japanese hand planes or kannas are remarkable tools that can shave off layers of wood so ridiculously thin that they look like tissue paper. The wood shaving in the GIF above is only 8 microns thick which almost sounds like an impossible measurement because even human hair has a diameter of about 50 microns.


21 Oct 07:16

Comic: Alien Tongues

by Tycho@penny-arcade.com (Tycho)
New Comic: Alien Tongues
20 Oct 08:47

Trump's Attempt To Refocus Campaign Gets Obscured By One Blinding Final Debate Moment

by Ron Elving

Donald Trump refused to say he would honor election results and was unsuccessful in changing the narrative that is enveloping his campaign. Hillary Clinton fired as many taunts as Trump landed blows.

20 Oct 07:00

6 Classic Shows (That Went Insane For One Episode)

By JM McNab  Published: October 20th, 2016 
20 Oct 11:16

De un garaje de Elche al espacio

espacio-tRaúl Torres y Raúl Verdú fabricaron su primer prototipo de cohete en un garaje de Elche. Hoy, estos dos jóvenes ingenieros lideran una start-up que ha conseguido desarrollar y probar tecnología puntera única en España. En Elche (Alicante) miran hacia arriba!.

espacio1más info +VICE

The post De un garaje de Elche al espacio appeared first on Yonkis.com.

21 Oct 15:30

An Innocent Tinder Hookup Takes One Heck of a Turn


Or...this is how you miss a layup after hitting a half-court shot.

Submitted by: (via Jakefiz)

20 Oct 18:16

[Review] Metal-catalyzed reductive coupling of olefin-derived nucleophiles: Reinventing carbonyl addition

by Khoa D. Nguyen
α-Olefins are the most abundant petrochemical feedstock beyond alkanes, yet their use in commodity chemical manufacture is largely focused on polymerization and hydroformylation. The development of byproduct-free catalytic C–C bond–forming reactions that convert olefins to value-added products remains an important objective. Here, we review catalytic intermolecular reductive couplings of unactivated and activated olefin-derived nucleophiles with carbonyl partners. These processes represent an alternative to the longstanding use of stoichiometric organometallic reagents in carbonyl addition. Authors: Khoa D. Nguyen, Boyoung Y. Park, Tom Luong, Hiroki Sato, Victoria J. Garza, Michael J. Krische
22 Oct 14:38

Saturday Morning Breakfast Cereal - Terrible News

by tech@thehiveworks.com


New comic!
Today's News:

We are nearly sold out of tickets for BAHFest West!

21 Oct 07:30

ortho-C−H Arylation of Benzoic Acids with Aryl Bromides and Chlorides Catalyzed by Ruthenium

by Agostino Biafora, Thilo Krause, Dagmar Hackenberger, Florian Belitz, Lukas J. Gooßen


A system consisting of catalytic amounts of [(p-cym)RuCl2]2/PEt3⋅HBF4, K2CO3 as the base, and NMP as the solvent efficiently mediates the ortho-C−H arylation of benzoic acids with aryl bromides at 100 °C. Replacing the phosphine ligand with the amino acid dl-pipecolinic acid enables the analogous transformation with aryl chlorides. The key advantage of this broadly applicable transformation is the use of an inexpensive ruthenium catalyst in combination with simple carboxylates as directing groups, which can either be tracelessly removed or used as anchor points for decarboxylative ipso substitutions.

Thumbnail image of graphical abstract

Bromides and chlorides: A system consisting of [(p-cym)RuCl2]2/PEt3⋅HBF4 as the catalyst, K2CO3 as the base, and NMP as the solvent efficiently mediates the ortho-C−H arylation of benzoic acids with aryl bromides at 100 °C. Replacing the phosphine ligand with the amino acid dl-pipecolinic acid enables the analogous transformation with aryl chlorides.

21 Oct 18:30

Several Sites Including Twitter, Spotify, PayPal, NYTimes Suffering Outage -- Dyn DNS Under DDoS Attack [Update]

by msmash
Several popular websites and services are down right now for many users. The affected sites include Twitter, SoundCloud, Spotify, and PayPal among others. The cause appears to be a sweeping outage of DNS provider Dyn -- which in turn is under DDoS attack, according to an official blog post.From a TechCrunch report: Other sites experiencing issues include Box, Boston Globe, New York Times, Github, Airbnb, Reddit, Freshbooks, Heroku and Vox Media properties. Users accessing these sites might have more or less success depending on where they're located, as some European and Asian users seem not to be encountering these issues.Last month, Bruce Schneier warned that someone was learning how to take down the internet. Update: 10/21 14:41 GMT by M :Dyn says that it has resolved the issue and sites should function normally.Update: 10/21 17:04 GMT by M :Department of Homeland Security says it is aware of the first DDoS attack on Dyn today and "investigating all potential causes." Dyn says it is still under DDoS attack. News outlet The Next Web says it is also facing issues. Any website that uses Dyn's service -- directly or indirectly -- is facing the issue. Motherboard has more details.Update: 10/21 17:57 GMT by M :It seems even PlayStation Network is also hit. EA Sports Games said it is aware of the issues in live-play. Dyn says it is facing a second round of DDoS attack. Update: 10/21 18:45 GMT by M :Reuters reports: U.S. government probing whether east coast internet attack was a 'criminal act' - official. Editor's note: the story is being updated as we learn more. The front page was updated to move this story up. Are you also facing issues? Share your experience in the comments section below.

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21 Oct 08:36

SSSS page 623

Page 623 is up!
20 Oct 23:32

Learn Three Magic Tricks You Can Easily Do With a Pen

by Casey Chan on Sploid, shared by Casey Chan to Gizmodo
Learn Three Magic Tricks You Can Easily Do With a Pen

Magic is mostly just how good you are with your hands. Here are three really easy magic tricks that you can pull with just a pen: making it disappear, making it appear out of nowhere, and making it look super small. Oscar Owen breaks down the techniques for each and they only involve super quick finger movements. The alternate angle reveals how easy it is.


20 Oct 16:58

How To Do The Bare Minimum Of Car Maintenance In Six Easy Steps

by Andrew P Collins on The Garage, shared by Alan Henry to Lifehacker

You don’t need a comprehensive understanding of how a car works to enjoy one. (Though I think it does help.) Anybody can make their car a lot safer and likely longer-lasting by paying attention to just a few key things, as this video runs through.


21 Oct 12:36

This Is Why Half the Internet Shut Down Today [Update: It’s Getting Worse]

by William Turton on Gizmodo, shared by Andy Orin to Lifehacker

Twitter, Spotify and Reddit, and a huge swath of other websites were down or screwed up this morning. This was happening as hackers unleashed a large distributed denial of service (DDoS) attack on the servers of Dyn, a major DNS host. It’s probably safe to assume that the two situations are related.


21 Oct 21:15

What Would Happen If a Presidental Candidate Refuses to Concede?

by Thorin Klosowski

In the final presidential debate, Donald Trump suggested that if he lost, he might not accept the results of the election and would not concede to Hillary Clinton. But is a concession actually required to finalize an election?


22 Oct 14:38

Saturday Morning Breakfast Cereal - Terrible News

by tech@thehiveworks.com


New comic!
Today's News:

We are nearly sold out of tickets for BAHFest West!