22 Jul 13:27

Development of Enantiospecific Coupling of Secondary and Tertiary Boronic Esters with Aromatic Compounds

by Marcin Odachowski, Amadeu Bonet, Stephanie Essafi, Philip Conti-Ramsden, Jeremy N. Harvey, Daniele Leonori and Varinder K. Aggarwal

TOC Graphic

Journal of the American Chemical Society
DOI: 10.1021/jacs.6b03963
22 Jul 07:22

Comic: The Tooth Hurts

by Tycho@penny-arcade.com (Tycho)
New Comic: The Tooth Hurts
20 Jul 17:00

How to Jailbreak Your Kindle

by Thorin Klosowski

Last week we learned you can jailbreak every current model of Kindle. Even better, while the process is a bit time-consuming, it’s also pretty easy to do. The end result is a Kindle that’s a little more pleasurable to use. Here’s how to do it.

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20 Jul 11:32

Light-Mediated Manufacture and Manipulation of Actuators

by Dong-Dong Han, Yong-Lai Zhang, Jia-Nan Ma, Yu-Qing Liu, Bing Han, Hong-Bo Sun

Recent years have seen a considerable growth of research interests in developing novel technologies that permit designable manufacture and controllable manipulation of actuators. Among various fabrication and driving strategies, light has emerged as an enabler to reach this end, contributing to the development of actuators. Several accessible light-mediated manufacturing technologies, such as ultraviolet (UV) lithography and direct laser writing (DLW), are summarized. A series of light-driven strategies including optical trapping, photochemical actuation, and photothermal actuation for controllable manipulation of actuators is introduced. Current challenges and future perspectives of this field are discussed. To generalize, light holds great promise for the development of actuators.

Thumbnail image of graphical abstract

Recent advances in light-mediated manufacture and manipulation of actuators are highlighted. Several optical fabrication technologies, including UV lithography and direct laser writing, and various photo-driven strategies, such as optical trapping, photochemical and photothermal actuation are reviewed. Emerging trends and future perspectives of light-enabled actuators are discussed.

20 Jul 21:25

This Guy Fell Off a Waterslide and Down A Rocky Cliff But He's Fine, Everything Is Fine

by Matt Novak

It’s basically every water slider’s worst nightmare. You don’t want to fall off. But you couldn’t fall off, right? The people who design waterslides wouldn’t let that happen. Right? Well, one guy from Dallas learned the hard way that you can’t trust anybody these days. Especially waterslide designers.

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20 Jul 16:58

Wednesday assorted links

by Tyler Cowen

1. A survey of the evidence on alphabetic discrimination.  It is real.

2. What went wrong with the Concorde?

3. Where does the New Jersey Italian-American accent come from?

4. Data on retirement insecurity: “The percentage of workers very confident about having enough money for a comfortable retirement, at record lows between 2009 and 2013, increased from 13 percent in 2013 to 22 percent in 2015, and, in 2016 has leveled off at 21 percent. The percentage of workers somewhat confident increased from 36 percent in 2015 to 42 percent in 2016, while the percentage not at all confident decreased from 24 percent in 2015 to 19 percent in 2016.”  And here is a complex discussion of SSA estimates.

5. The new science of cute the culture that is Japan — “Nobody is cute in Shakespeare.”

6. “It seems to me that news events over the past twelve months or so have put a strain on those who are inclined to view human nature as good.

The post Wednesday assorted links appeared first on Marginal REVOLUTION.

20 Jul 13:08

Encapsulating a Co(II) Molecular Photocatalyst in Metal–Organic Framework for Visible-Light-Driven H2 Production: Boosting Catalytic Efficiency via Spatial Charge Separation

by Zhe Li, Juan-Ding Xiao and Hai-Long Jiang

TOC Graphic

ACS Catalysis
DOI: 10.1021/acscatal.6b01293
22 Jul 06:20

Oxidative Difunctionalization of Alkenyl MIDA Boronates: A Versatile Platform for Halogenated and Trifluoromethylated α-Boryl Ketones

by Wen-Xin Lv, Yao-Fu Zeng, Qingjiang Li, Yunyun Chen, Dong-Hang Tan, Ling Yang, Honggen Wang

Abstract

The synthesis of halogenated and trifluoromethylated α-boryl ketones via a one-pot oxidative difunctionalization of alkenyl MIDA boronates is reported. These novel densely functionalized organoborons bearing synthetically and functionally valuable carbonyl, halogen/CF3 and boronate moieties within the same molecule are synthetically challenging for the chemist, but have great synthetic potential, as demonstrated by their applications in a straightforward synthesis of borylated furans. The generality of this reaction was extensively investigated. This reaction is attractive since the starting materials, alkenyl MIDA boronates, are easily accessible.

Thumbnail image of graphical abstract

α-Boryl ketone synthesis: A one-pot oxidative difunctionalization of alkenyl MIDA boronates for the syntheses of densely functionalized α-boryl ketones was developed. The presence of multiple functional groups within the same molecule confers on these products great synthetic utility, as demonstrated by the successful synthesis of borylated furans.

20 Jul 16:58

Wednesday assorted links

by Tyler Cowen

1. A survey of the evidence on alphabetic discrimination.  It is real.

2. What went wrong with the Concorde?

3. Where does the New Jersey Italian-American accent come from?

4. Data on retirement insecurity: “The percentage of workers very confident about having enough money for a comfortable retirement, at record lows between 2009 and 2013, increased from 13 percent in 2013 to 22 percent in 2015, and, in 2016 has leveled off at 21 percent. The percentage of workers somewhat confident increased from 36 percent in 2015 to 42 percent in 2016, while the percentage not at all confident decreased from 24 percent in 2015 to 19 percent in 2016.”  And here is a complex discussion of SSA estimates.

5. The new science of cute the culture that is Japan — “Nobody is cute in Shakespeare.”

6. “It seems to me that news events over the past twelve months or so have put a strain on those who are inclined to view human nature as good.

The post Wednesday assorted links appeared first on Marginal REVOLUTION.

20 Jul 13:11

Efficient Conversion of Methane to Aromatics by Coupling Methylation Reaction

by Yi Liu, Defu Li, Tianyun Wang, Yang Liu, Teng Xu and Yi Zhang

TOC Graphic

ACS Catalysis
DOI: 10.1021/acscatal.6b01362
20 Jul 13:00

Skype finalizes its move to the cloud, ignores the elephant in the room

by Peter Bright

The new UWP Skype client. (credit: Microsoft)

It has been a slow transition, but Skype is finalizing its move away from a peer-to-peer system to a cloud-based one.

When it was first created, the Skype network was built as a decentralized peer-to-peer system. PCs that had enough processing power and bandwidth would be elected as "supernodes" and used to coordinate connections between other machines on the network. Similarly, text, voice, and video traffic would flow between peers, directly when possible (when intervening firewalls and routers were cooperative) or indirectly through other systems on the network when required.

This peer-to-peer system was generally perceived as being relatively private; with no central servers the assumption was that there was no central ability to perform wiretaps or other forms of eavesdropping. This belief was in fact mistaken.

Read 18 remaining paragraphs | Comments

21 Jul 20:40

'The Wolf of Wall Street' Movie Was Financed With Stolen Money, Says DOJ

by BeauHD
An anonymous reader quotes a report from NY Daily News: Federal officials charged a $3.5 billion Malaysian money-laundering scheme helped finance the Leonardo DiCaprio movie "Wolf of Wall Street" -- the Hollywood tale that parallels the corruption charges. U.S. officials seek to recover $1.3 billion of the missing funds, including profits from the Martin Scorsese-directed movie that earned five Oscar nominations. The conspirators used some of their illicit cash to fund Scorsese's tale of "a corrupt stockbroker who tried to hide his own illicit profits in a perceived foreign safe haven," said U.S. Assistant Attorney General Leslie Caldwell. DiCaprio famously played the lead role of convicted fraudster Jordan Belfort, who was ordered to repay $110 million to 1,500 victims of his scam. The identified conspirators included movie producer Riza Shahriz Abdul Aziz, the prime minister's stepson, and businessman Low Taek John, a friend of Najib's family. A third scammer identified only as "Malaysian Official 1" was widely believed to be Najib. Court papers indicated that $681 million from a 2013 bond sale went directly into the official's private account. The nation's attorney-general, Mohamed Apandi, came to Najib's defense Thursday, expressing his "strong concerns at the insinuations and allegations" brought against the 1Malaysia Development Berhad (1MDB). Apandi's office, after investigating the $681 million bank deposit, announced in January that the funds were a donation from the Saudi royal family. The prime minister wound up returning most of the cash. Federal officials, in their California court filing, indicated they were hoping to seize proceeds from the 2013 movie, along with luxury properties in New York and California, artwork by Vincent Van Gogh and Claude Monet, and a $35 million private jet. Investigations of 1MDB are already underway in Switzerland and Singapore, with officials in the latter announcing Thursday that they had seized assets worth $176 million. This is shaping up to be the largest U.S. Justice Department asset recovery action in history.

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21 Jul 11:16

Apple and Facebook helped bust the world's biggest torrent site

by Matt Brian
When you're the owner of the world's biggest torrent-sharing site, the last thing you'd expect to land you in trouble would be a totally legitimate (and legal) purchase via iTunes. But that's what happened to 30-year-old Ukrainian Artem Vaulin a.k.a...
21 Jul 09:32

Overcoming the Limitations of C−H Activation with Strongly Coordinating N-Heterocycles by Cobalt Catalysis

by Hui Wang, Mélanie M. Lorion, Lutz Ackermann

Abstract

Strongly coordinating nitrogen heterocycles, including pyrimidines, oxazolines, pyrazoles, and pyridines, were fully tolerated in cobalt-catalyzed C−H amidations by imidate assistance. Structurally complex quinazolines are thus accessible in a step-economic manner. Our findings also establish the relative powers of directing groups in cobalt(III)-catalyzed C−H functionalization for the first time.

Thumbnail image of graphical abstract

Strongly coordinating nitrogen heterocycles are fully tolerated by a versatile cobalt-catalyzed C−H amidation method, which provides access to structurally complex quinazolines. The powers of various directing groups in cobalt-catalyzed C−H activation were thus delineated.

20 Jul 18:45

‘The Internet Is Turning Us All Into Sociopaths’

by John Gruber

Archived 2012 piece from the now-defunct The Kernel:

What’s disturbing about this new trend, in which commenters are posting what would previously have been left anonymously, is that these trolls seem not to mind that their real names, and sometimes even their occupations, appear clamped to their vile words. It’s as if a psychological norm is being established whereby comments left online are part of a video game and not real life. It’s as if we’ve all forgotten that there’s a real person on the other end, reading and being hurt by our vitriol. That’s as close to the definition of sociopath as one needs to get for an armchair diagnosis, though of course many other typical sociopathic traits are also being encouraged by social media.

Well-said. But the kicker is the byline.

(Via Charles Arthur.)

20 Jul 12:54

Comic for Wednesday, July 20th, 2016

Comic for Wednesday, July 20th, 2016 is located at http://twokinds.keenspot.com/
22 Jul 00:42

Friends Don’t Let Friends Read Andrew Sullivan, Part [n]

by Tom Levenson

Further to my disdain below, I can’t say anything to gloss what Andrew writes in tonight’s RNC liveblog.

MSKG - De idioot bij de vijver - Frits Van den Berghe (1926)

Truly, all you need to know about Andrew’s political and intellectual honesty is right there:

8:18 p.m. We have to answer this core question: how is it that liberal democracy in America is now flirting with strongman, ethno-nationalist authoritarianism? What happened to the democratic center?

It seems to me that the right bears the hefty majority of responsibility, moving from principled opposition to outright nullification of a presidency, trashing every important neutral institution, and now bad-mouthing the country they hope to “govern.” But the left’s abandonment of empiricism and liberalism – its rapid descent into neo-Marxist dogma, its portrayal of American history as a long unending story of white supremacy, its coarse impugning of political compromise and incrementalism, its facile equation of disagreement with bigotry – has also played a part. Liberal democracy needs liberal norms and manners to survive. Which is why it is now on life-support.

In between, moderate Christianity, once a unifying cultural fabric creating a fragile civil discourse, has evaporated into disparate spirituality on one side and fundamentalist dogma on the other, leaving us with little in the center to hold us morally together.

Annnnd, Scene!

Have at it, friends.

Image:  Frits Van den Berghe, The Idiot by the Pond1926

20 Jul 14:36

What can we do

by The Awkward Yeti

0716_ScaryWorld

21 Jul 05:00

Menage a 3 - That was

Menage a 3 - That was
22 Jul 05:36

Girls With Slingshots - GWS Chaser #359

by tech@thehiveworks.com
New comic!
Today's News:

Is this the first time Jamie and Hazel fight in the strip? And over a wig and cardboard boobs, naturally.

http://www.girlswithslingshots.com//comic/gws359">Here's the old strip!

21 Jul 15:59

Visible-Light-Driven Selective Photocatalytic Hydrogenation of Cinnamaldehyde over Au/SiC Catalysts

by Cai-Hong Hao, Xiao-Ning Guo, Yung-Tin Pan, Shuai Chen, Zhi-Feng Jiao, Hong Yang and Xiang-Yun Guo

TOC Graphic

Journal of the American Chemical Society
DOI: 10.1021/jacs.6b04175
21 Jul 04:00

1002

by Ed Ryzowski

lfg3618-1002-jul21-16

The post 1002 appeared first on Looking For Group.

20 Jul 20:05

Engineer Gets Tired Of Waiting For Telecom Companies To Wire His town -- So He Does It Himself

by manishs
Gurb, 75 kilometers north of Barcelona, is a quiet farming community of 2,500. It has suddenly become a popular place, thanks to being the birthplace of Guifi.net, one of the world's "most important experiments in telecommunications." It was built by an engineer who got tired of waiting for Telefonica, the Spanish telecom giant, to provide internet access to the people of his community. At first he wanted an internet access for himself, but it soon became clear that he also wanted to help his neighbors. Guifi has grown from a single wifi node in 2004, to 30,000 working nodes today, including some fiber connections, with thousands more in the planning stages. An article on Backchannel today documents the tale of Guifi. From the article: The project is a testament to tireless efforts -- in governance, not just in adding hardware and software -- by Ramon Roca (the engineer who started it) and his colleagues. They've been unwavering in their commitment to open access, community control, network neutrality, and sustainability. In 2004, he bought some Linksys WiFI hackable routers with a mission to get himself and his neighbors connected to the Internet. This is how he did it: Roca turned on a router with a directional antenna he'd installed at the top of a tall building near the local government headquarters, the only place in town with Internet access -- a DSL line Telefonica had run to municipal governments throughout the region. The antenna was aimed, line of sight, toward Roca's home about six kilometers away. Soon, neighbors started asking for connections, and neighbors of neighbors, and so on. Beyond the cost of the router, access was free. Some nodes were turned into "supernodes" -- banks of routers in certain locations, or dedicated gear that accomplishes the same thing -- that could handle much more traffic in more robust ways. The network connected to high-capacity fiber optic lines, to handle the growing demand, and later connected to a major "peering" connection to the global Internet backbone that provides massive bandwidth. Guifi grew, and grew, and grew. But soon it became clear that connecting more and more nodes wasn't enough, so he created a not-for-profit entity, the Guifi.net Foundation. The foundation, thanks to its cause and a cheerful community, has received over a million Euros to date -- from various sources including several levels of government. But as the article notes, a million Euros is a drop in the bucket next to the lavish subsidies and favors that state-approved monopolies such as Telefonica have enjoyed for decades. The article adds: The Guifi Foundation isn't the paid provider of most Internet service to end-user (home and business) customers. That role falls to more than 20 for-profit internet service providers that operate on the overall platform. The ISPs share infrastructure costs according to how much demand they put on the overall system. They pay fees to the foundation for its services -- a key source of funding for the overall project. Then they offer various kinds of services to end users, such as installing connections -- lately they've been install fiber-optic access in some communities -- managing traffic flows, offering email, handling customer and technical support, and so on. The prices these ISPs charge are, to this American (Editor's note: the author is referring to himself) who's accustomed to broadband-cartel greed, staggeringly inexpensive: 18 to 35 Euros (currently about $26-$37) a month for gigabit fiber, and much less for slower WiFi. Community ownership and ISP competition does wonders for affordability. Contrast this with the U.S. broadband system, where competitive dial-up phone access -- phone companies were obliged to let all ISPs use the lines as the early commercial Internet flourished in the 1990s -- gave way to a cartel of DSL and cable providers. Except in a few places where there's actual competition, we pay way more for much less.Read the story in its entirety here.

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21 Jul 12:30

Enable a Hidden Dark Theme In Windows 10 Apps With a Registry Edit

by Eric Ravenscraft

Windows 10's interface is pretty slick, but if you’re not a fan of bright colors on your screen, it might be a little hard on the eyes. You can switch to a darker theme for many system apps with a little tweak.

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