HEY, I LOVE LISTS!
- How to an artist according to Georgia O’Keefe
- Your horoscope affirmations for March.
- Summer dresses to daydream about: one / two / three
- This is so dang clever.
- Oh nooooo Necco!
- I don’t think I’d mind living in a 175 square foot apt.
- 19 kinds of reading you’ve done– I loved this.
- When in doubt, swear it out.
- The Milky Way is beautiful.
- Why does this sound super gross to me?
- No, I will not try platypus milk.
- This is the way introverts pick their person.
- Most Underrated/Overrated things from Trader Joe’s
- 10 Most Famous Bookstores in the World
- People doing awesome things with their computer wallpaper.
- New music by Leon Bridges! YES.
- Omg online shopping fails.
- Nail inspiration!
- What Stage IV Cancer Taught Me
- Molly makes everything beautiful. Check out her dining room.
- Instagram is not turning back into a chronological feed. Boo
- I think my mother-in-law would love this.
- How did I know I’d get Rowlf??
- How people kicked some of their bad habits.
- Stephen Hawkings was funny.
- You won’t look like Sharon Stone at 59.
My pre-release copy of Pretty Dish. Very excited about this cookbook! Jessica does not disappoint.
Finding my mom’s nail polish and wearing it.
The light outside at night!! Thank you daylight savings….even though it’s so dark in the mornings.
Listening to Kenny Loggins on Spotify
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Hey geeks, my nephew has gone missing as of last Saturday. He's 15, 6'2", probably in Massachusetts, probably in the Framinham or Dorchester area. We are very worried and upset - if you could please share this link, we would very much appreciate it.
Ring expansion and re-contraction for the synthesis of 1-aryl tetrahydroisoquinolines and tetrahydrobenzazepines from readily available heterocyclic precursors
Tetrahydroisoquinolines and tetrahydrobenzazepines are prepared by acid-promoted ring contraction of cyclic ureas, themselves formed by ring expansion of indolines and tetrahydroquinolines. The consequent overall one-carbon insertion reaction gives these 6- and 7-membered heterocyclic scaffolds in three steps from readily available precursors. Other ring sizes may be formed by an alternative elimination reaction of bicyclic structures. Scalability of the method was demonstrated by operating it in a flow system.
Read more of this story at Slashdot.
We’d hardly call ourselves hardcore Potterverse fans, but it seems to us there’s more than a bit of fan unrest regarding this picture. From the apparent light de-gaying of the Dumbledore character to the rather poor attempts at explaining why the film cast Johnny Depp in the title role, it feels more and more like this one’s coming out of the gate with a strong headwind against it.
We can’t say we have strong feelings about it either way, since the first Fantastic Beasts film was little more than a charming bit of forgettable fantasy, from where we were sitting. But no matter how ambivalent we may have been about the sequel or how irritating we tend to find Eddie Redmayne or how questionable we find the appeal of Johnny Depp…
…it sure is pretty to look at.
What can we say? That lovely clash of early 20th Century clothing styles with fantasy design tropes is our costume design sweet spot. It gets us all a-tingle, darlings – but only when it’s done well. Fortunately, they handed the reins over to highly lauded and awarded costume designer Colleen Atwood, who knows a thing or two about how to spin a believable fantasy out of costume design.
Also, Jude Law is looking FOINE, which is a bit of a double-edged sword, because he’s basically Hot, But Sexless Dumbledore in this one, if the rumors are to be believed. Oh, well. We’ll just look at the clothes.
Warner Bros. Pictures’ “Fantastic Beasts: The Crimes of Grindelwald” is the second of five all new adventures in J.K. Rowling’s Wizarding World.
At the end of the first film, the powerful Dark wizard Gellert Grindelwald (Johnny Depp) was captured by MACUSA (Magical Congress of the United States of America), with the help of Newt Scamander (Eddie Redmayne). But, making good on his threat, Grindelwald escaped custody and has set about gathering followers, most unsuspecting of his true agenda: to raise pure-blood wizards up to rule over all non-magical beings.
In an effort to thwart Grindelwald’s plans, Albus Dumbledore (Jude Law) enlists his former student Newt Scamander, who agrees to help, unaware of the dangers that lie ahead. Lines are drawn as love and loyalty are tested, even among the truest friends and family, in an increasingly divided wizarding world.
The film features an ensemble cast led by Eddie Redmayne, Katherine Waterston, Dan Fogler, Alison Sudol, Ezra Miller, with Jude Law and Johnny Depp. The cast also includes, Zoë Kravitz, Callum Turner, Claudia Kim, William Nadylam, Kevin Guthrie, Carmen Ejogo, and Poppy Corby-Tuech.
“Fantastic Beasts: The Crimes of Grindelwald” is directed by David Yates, from a screenplay by J.K. Rowling. The film is produced by David Heyman, J.K. Rowling, Steve Kloves and Lionel Wigram.
Slated for release on November 16, 2018, the film will be distributed worldwide in 2D and 3D in select theatres and IMAX by Warner Bros. Pictures, a Warner Bros. Entertainment.
[Photo Credit: Jaap Buitendijk/Warner Bros. – Video Credit: via YouTube.com]
The post If Nothing Else, “Fantastic Beasts: The Crimes of Grindelwald” Will Give Us Costume Porn appeared first on Tom + Lorenzo.
Incorporation of Imidazolium-Based Poly(ionic liquid)s into a Metal–Organic Framework for CO2 Capture and Conversion
Synthesis and Characterization of a Bidirectional Photoswitchable Antagonist Toolbox for Real-Time GPCR Photopharmacology
Though Halloween, with its trick-or-treaters and grab bags of bulk candy, and Valentine’s Day, with its heart-shaped boxes of chocolate, get most of the sugary glory, the truly candy-obsessed know that the best holiday for candy consumption is Easter. (If you don’t believe me, know that in 2016, more Americans bought candy for Easter than for Halloween.) It’s the time for Easter baskets full of chocolate bunnies, chocolate Easter eggs, and, of course, marshmallow Peeps. And to help you find the best Easter chocolate and Easter candy to put in your family’s baskets this year (or your own, we don’t judge), we asked 11 chefs, from New York and Miami, to share their favorite Easter chocolates, candies, and treats.
The Strategist is designed to surface the most useful, expert recommendations for things to buy across the vast e-commerce landscape. Some of our latest conquests include the best dining room decor items, coffee makers, knife sets, Japanese coffee brewer, charcoal water filter, and drinking glasses for water and more. We update links when possible, but note that deals can expire and all prices are subject to change.
Every editorial product is independently selected. If you buy something through our links, New York may earn an affiliate commission.
With the rapid development of mobile electronics and electric vehicles, future electrochemical capacitors (ECs) need to store as much energy as possible in a rather limited space. As the core component of ECs, dense electrodes that have a high volumetric energy density and superior rate capability are the key to achieving improved energy storage. Here, the significance of and recent progress in the high volumetric performance of dense electrodes are presented. Furthermore, dense yet porous electrodes, as the critical precondition for realizing superior electrochemical capacitive energy, have become a scientific challenge and an attractive research focus. From a pore-engineering perspective, insight into the guidelines of engineering the pore size, connectivity, and wettability is provided to design dense electrodes with different porous architectures toward high-performance capacitive energy storage. The current challenges and future opportunities toward dense electrodes are discussed and include the construction of an orderly porous structure with an appropriate gradient, the coupling of pore sizes with the solvated cations and anions, and the design of coupled pores with diverse electrolyte ions.
Dense yet porous electrodes with high volumetric performance are the key to achieving superior electrochemical capacitive energy storage. Significant research breakthroughs in the volumetric performance of dense electrodes are presented. In particular, an insight into the guidelines of pore engineering is provided, to allow the design of dense electrodes toward high-performance energy storage.
Novel click reactions are of continued interest in fields as diverse as bio-conjugation, polymer science and surface chemistry. Qualification as a proper 'click' reaction requires stringent criteria, including fast kinetics and high conversion, to be met. Herein, we report a novel strain-promoted cycloaddition between cyclopropenes and o-quinones in solution and on a surface. We demonstrate the 'click character' of the reaction in solution and on surfaces for both monolayer and polymer brush functionalization.
Read more of this story at Slashdot.
Monolayer Nanosheets with an Extremely High Drug Loading toward Controlled Delivery and Cancer Theranostics
2D nanomaterials have attracted considerable research interest in drug delivery systems, owing to their intriguing quantum size and surface effect. Herein, Gd3+-doped monolayered-double-hydroxide (MLDH) nanosheets are prepared via a facile bottom-up synthesis method, with a precisely controlled composition and uniform morphology. MLDH nanosheets as drug carrier are demonstrated in coloading of doxorubicin and indocyanine green (DOX&ICG), with an ultrahigh drug loading content (LC) of 797.36% and an encapsulation efficiency (EE) of 99.67%. This is, as far as it is known, the highest LC level at nearly 100% of EE among previously reported 2D drug delivery systems so far. Interestingly, the as-prepared DOX&ICG/MLDH composite material shows both pH-controlled and near-infrared-irradiation-induced DOX release, which holds a promise in stimulated drug release. An in vivo dual-mode imaging, including near-infrared fluorescence and magnetic resonance imaging, enables a noninvasive visualization of distribution profiles at the tumor site. In addition, in vitro and in vivo therapeutic evaluations demonstrate an excellent trimode synergetic anticancer activity and superior biocompatibility of DOX&ICG/MLDH. Therefore, MLDH nanosheets provide new perspectives in the design of multifunctional nanomedicine, which shows promising applications in controlled drug delivery and cancer theranostics.
Gd3+-doped monolayered-double-hydroxide (MLDH) nanosheets are prepared via a new bottom-up synthesis method followed by the coloading of doxorubicin and indocyanine green, with an ultrahigh drug loading content of 797.36% and encapsulation efficiency of 99.67%. In addition, both in vitro and in vivo studies demonstrate an excellent dual-mode imaging and trimode synergetic therapy toward cancer theranostics.
AUSTIN, Texas—The five-person team behind a simple WordPress plugin, which took three hours to code, never expected to receive worldwide attention as a result. But NRKbeta, the tech-testing group at Norway's largest national media organization, tapped into a meaty vein with the unveiling of last February's Know2Comment, an open source plugin that can attach to any WordPress site's comment section.
"It was a basic idea," NRKbeta developer Ståle Grut told a South By Southwest crowd on Tuesday. "Readers had to prove they read a story before they were able to comment on it."
The story has since been told a few times, but Grut's recent refresh on the topic is just as compelling for its comment-section impact as it is for NRK's thought process on how to make Internet media a better place: invite readers to have an active stake in improving it.
Small Molecule Interactome Mapping by Photoaffinity Labeling Reveals Binding Site Hotspots for the NSAIDs
Theoretical and Experimental Insight into the Effect of Nitrogen Doping on Hydrogen Evolution Activity of Ni3S2 in Alkaline Medium
Nickel sulfide (Ni3S2) is a promising hydrogen evolution reaction (HER) catalyst by virtue of its metallic electrical conductivity and excellent stability in alkaline medium. However, the reported catalytic activities for Ni3S2 are still relatively low. Herein, an effective strategy to boost the H adsorption capability and HER performance of Ni3S2 through nitrogen (N) doping is demonstrated. N-doped Ni3S2 nanosheets achieve a fairly low overpotential of 155 mV at 10 mA cm−2 and an excellent exchange current density of 0.42 mA cm−2 in 1.0 m KOH electrolyte. The mass activity of 16.9 mA mg−1 and turnover frequency of 2.4 s−1 obtained at 155 mV are significantly higher than the values reported for other Ni3S2-based HER catalysts, and comparable to the performance of best HER catalysts in alkaline medium. These experimental data together with theoretical analysis suggest that the outstanding catalytic activity of N-doped Ni3S2 is due to the enriched active sites with favorable H adsorption free energy. The activity in the Ni3S2 is highly correlated with the coordination number of the surface S atoms and the charge depletion of neighbor Ni atoms. These new findings provide important guidance for future experimental design and synthesis of optimal HER catalysts.
Nitrogen-doped Ni3S2 nanosheets achieve excellent hydrogen evolution reaction (HER) performance in alkaline media. Both experimental and theoretical investigations suggest that the improved activity of nitrogen-doped Ni3S2 originates from enriched new active sites with favorable H adsorption. These new findings make inexpensive Ni3S2 more attractive and provide important guidance for future experimental design and synthesis of Ni3S2-based HER catalysts.