Shared posts

08 Nov 12:52

[ASAP] Multifunctional Transferrin Encapsulated GdF3 Nanoparticles for Sentinel Lymph Node and Tumor Imaging

by Xudong Shi, Kai Gao, Shaoqing Xiong, and Ran Gao

TOC Graphic

Bioconjugate Chemistry
DOI: 10.1021/acs.bioconjchem.0c00514
24 Oct 01:57

Reversibility and reactivity in an acid catalyzed cyclocondensation to give furanochromanes – a reaction at the ‘oxonium-Prins’ vs. ‘ortho-quinone methide cycloaddition’ mechanistic nexus

Chem. Sci., 2019, 10,406-412
DOI: 10.1039/C8SC04302G, Edge Article
Open Access Open Access
Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Christian D.-T. Nielsen, Wouter J. Mooij, David Sale, Henry S. Rzepa, Jordi Burés, Alan C. Spivey
Herein we report a combined experimental and computational investigation of the acid catalyzed cyclocondensation reaction between styrenyl homoallylic alcohols and salicylaldehyde to form furanochromanes.
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25 Nov 10:39

Reduced high-frequency motor neuron firing, EMG fractionation, and gait variability in awake walking ALS mice [Neuroscience]

by Muhamed Hadzipasic, Weiming Ni, Maria Nagy, Natalie Steenrod, Matthew J. McGinley, Adi Kaushal, Eleanor Thomas, David A. McCormick, Arthur L. Horwich
Amyotrophic lateral sclerosis (ALS) is a lethal neurodegenerative disease prominently featuring motor neuron (MN) loss and paralysis. A recent study using whole-cell patch clamp recording of MNs in acute spinal cord slices from symptomatic adult ALS mice showed that the fastest firing MNs are preferentially lost. To measure the in...
03 Mar 08:01

Unintended consequences

Unintended consequences

Nature 531, 7592 (2016). doi:10.1038/531007a

After the introduction of a clumsily worded new rule, the UK government should move quickly to reassure scientists that they can continue to advise policymakers.

02 Feb 02:40

[Letter] The value of audiovisual archives

by Luís Felipe Toledo
Authors: Luís Felipe Toledo, Cheryl Tipp, Rafael Márquez