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07 Mar 02:36

Interfacial molecular engineering for enhanced polarization of negative tribo-materials

Publication date: 1 June 2022

Source: Nano Energy, Volume 96

Author(s): Wook Kim, Joon Hui Park, Hee Jae Hwang, You Seung Rim, Dukhyun Choi

08 Feb 12:13

Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression

by Zhang, K., Miorin, L., Makio, T., Dehghan, I., Gao, S., Xie, Y., Zhong, H., Esparza, M., Kehrer, T., Kumar, A., Hobman, T. C., Ptak, C., Gao, B., Minna, J. D., Chen, Z., Garcia-Sastre, A., Ren, Y., Wozniak, R. W., Fontoura, B. M. A.

The ongoing unprecedented severe acute respiratory syndrome caused by the SARS-CoV-2 outbreak worldwide has highlighted the need for understanding viral-host interactions involved in mechanisms of virulence. Here, we show that the virulence factor Nsp1 protein of SARS-CoV-2 interacts with the host messenger RNA (mRNA) export receptor heterodimer NXF1-NXT1, which is responsible for nuclear export of cellular mRNAs. Nsp1 prevents proper binding of NXF1 to mRNA export adaptors and NXF1 docking at the nuclear pore complex. As a result, a significant number of cellular mRNAs are retained in the nucleus during infection. Increased levels of NXF1 rescues the Nsp1-mediated mRNA export block and inhibits SARS-CoV-2 infection. Thus, antagonizing the Nsp1 inhibitory function on mRNA export may represent a strategy to restoring proper antiviral host gene expression in infected cells.

17 Sep 09:02

Tissue fluidity promotes epithelial wound healing

by Robert J. Tetley

Nature Physics, Published online: 12 August 2019; doi:10.1038/s41567-019-0618-1

An observation that cells at the edge of a healing wound readily undergo intercalation leads to the finding that tissue fluidity is crucial for effective wound closure.
08 Jan 05:44

A Ternary Fe1−xS@Porous Carbon Nanowires/Reduced Graphene Oxide Hybrid Film Electrode with Superior Volumetric and Gravimetric Capacities for Flexible Sodium Ion Batteries

by Yang Liu, Yongjin Fang, Zhiwei Zhao, Changzhou Yuan, Xiong Wen (David) Lou
Advanced Energy Materials A Ternary Fe1−xS@Porous Carbon Nanowires/Reduced Graphene Oxide Hybrid Film Electrode with Superior Volumetric and Gravimetric Capacities for Flexible Sodium Ion Batteries

A highly flexible Fe1− x S@PCNWs/rGO hybrid paper electrode with robust mechanical properties is successfully fabricated and shown to exhibit superior sodium storage properties with high volumetric and gravimetric capacities. Using this paper anode, a flexible sodium ion battery is also fabricated and shown to exhibit promising performance.


Abstract

Smart construction of ultraflexible electrodes with superior gravimetric and volumetric capacities is still challenging yet significant for sodium ion batteries (SIBs) toward wearable electronic devices. Herein, a hybrid film made of hierarchical Fe1− x S‐filled porous carbon nanowires/reduced graphene oxide (Fe1− x S@PCNWs/rGO) is synthesized through a facile assembly and sulfuration strategy. The resultant hybrid paper exhibits high flexibility and structural stability. The multidimensional paper architecture possesses several advantages, including rendering an efficient electron/ion transport network, buffering the volume expansion of Fe1− x S nanoparticles, mitigating the dissolution of polysulfides, and enabling superior kinetics toward efficient sodium storage. When evaluated as a self‐supporting anode for SIBs, the Fe1− x S@PCNWs/rGO paper electrode exhibits remarkable reversible capacities of 573–89 mAh g−1 over 100 consecutive cycles at 0.1 A g−1 with areal mass loadings of 0.9–11.2 mg cm−2 and high volumetric capacities of 424–180 mAh cm−3 in the current density range of 0.2–5 A g−1. More competitively, a SIB based on this flexible Fe1− x S@PCNWs/rGO anode demonstrates outstanding electrochemical properties, thus highlighting its enormous potential in versatile flexible and wearable applications.

05 Sep 00:39

High‐Temperature‐Triggered Thermally Degradable Electronics Based on Flexible Silicon Nanomembranes

by Gongjin Li , Enming Song , Gaoshan Huang , Qinglei Guo , Fei Ma , Bin Zhou , Yongfeng Mei
Advanced Functional Materials High‐Temperature‐Triggered Thermally Degradable Electronics Based on Flexible Silicon Nanomembranes

The integration of a high‐temperature degradable poly‐α‐methylstyrene interlayer enables a distinct and irreversible degradation process for flexible single crystal silicon nanomembrane devices at 300 °C. Systematic experiments and simulations reveal the failure mechanism. This work provides a foundation for understanding the transient mode of future on‐chip components in high‐temperature electronics.


Abstract

An advanced transient approach enables the sudden degradation and subsequent disappearance of device‐grade electronic systems on a temporary platform with limited remains over a desired period for long‐term stable operation. To satisfy the requirements for flexible devices in transient electronics capable of working at high temperature, transient Si‐nanomembrane (Si‐NM) electronics integrated with high‐temperature degradable poly‐α‐methylstyrene (PAMS) are presented. Systematic experimental studies suggest that a 4 µm thick PAMS interlayer in the Si‐NM device ensures stable operation below the decomposition temperature of PAMS (≈300 °C), while the device undergoes transient process when triggered at higher temperature. Experimental characterization and theoretical modeling reveal the essential properties of the flexible device and its failure mechanism. Demonstrations of such a transient component in high‐temperature electronics highlight the potential advantages in the demands for circuit safeguards, information security, and sensing/control systems.

20 Dec 00:27

Dual-Ion Batteries: Carbon-Coated Porous Aluminum Foil Anode for High-Rate, Long-Term Cycling Stability, and High Energy Density Dual-Ion Batteries (Adv. Mater. 45/2016)

by Xuefeng Tong, Fan Zhang, Bifa Ji, Maohua Sheng, Yongbing Tang
Thumbnail image of graphical abstract

On page 9979, a novel carbon coated porous Al foil as the anode and current collector for the dual-ion battery (DIB) is reported by Yongbing Tang and co-workers, which exhibits longterm cycling stability of over 1000 cycles with 89.4% retention at 2C. The energy density of this DIB is about 204 Wh kg−1 at a high power density of 3084 W kg−1, which is two times as large as most commercial lithium ion batteries.

15 Jun 11:35

Single-Site Cobalt Catalysts at New Zr12(μ3-O)8(μ3-OH)8(μ2-OH)6 Metal–Organic Framework Nodes for Highly Active Hydrogenation of Nitroarenes, Nitriles, and Isocyanides

by Pengfei Ji, Kuntal Manna, Zekai Lin, Xuanyu Feng, Ania Urban, Yang Song and Wenbin Lin

TOC Graphic

Journal of the American Chemical Society
DOI: 10.1021/jacs.7b02394
15 May 03:07

Catalytic Asymmetric [3+1]-Cycloaddition Reaction of Ylides with Electrophilic Metallo-enolcarbene Intermediates

by Yongming Deng, Lynée A. Massey, Peter Y. Zavalij, Michael P. Doyle

Abstract

The first asymmetric [3+1]-cycloaddition was successfully achieved by copper(I) triflate/double-sidearmed bisoxazoline complex catalyzed reactions of β-triisopropylsilyl-substituted enoldiazo compounds with sulfur ylides. This methodology delivered a series of chiral cyclobutenes in good yields with high enantio- and diastereoselectivities (up to 99 % ee, and >20:1 d.r.). Additionally, the [3+1]-cycloaddition of catalytically generated metallo-enolcarbenes was successfully extended to reaction with a stable benzylidene dichlororuthenium complex.

Thumbnail image of graphical abstract

Three plus one: β-Triisopropylsilyl-substituted enoldiazo compounds react with sulfur ylides in a [3+1]-cycloaddition reaction catalyzed by copper(I) triflate/double-sidearmed bisoxazoline complex (see figure) to give cyclobutenes. The asymmetric version proceeds in good yield with high enantio- and diastereoselectivity.

09 May 00:38

Precision-Trimming 2D Inverse-Opal Lattice on Elastomer to Ordered Nanostructures with Variable Size and Morphology

by Haoran Zhan, Yanqiu Chen, Yu Liu, Woonming Lau, Chao Bao, Minggan Li, Yunlong Lu, Jun Mei and David Hui

TOC Graphic

Langmuir
DOI: 10.1021/acs.langmuir.6b04409
14 Jun 06:18

Laboratory analogue of a supersonic accretion column in a binary star system

by J. E. Cross

Article

Stationary radiative shocks are expected to form above the surface of highly-magnetized white dwarves in binary systems, but this cannot be resolved by telescopes. Here, the authors report a laboratory experiment showing the evolution of a reverse shock when both ionization and radiative losses are important.

Nature Communications doi: 10.1038/ncomms11899

Authors: J. E. Cross, G. Gregori, J. M. Foster, P. Graham, J. -M. Bonnet-Bidaud, C. Busschaert, N. Charpentier, C. N. Danson, H. W. Doyle, R. P. Drake, J. Fyrth, E. T. Gumbrell, M. Koenig, C. Krauland, C. C. Kuranz, B. Loupias, C. Michaut, M. Mouchet, S. Patankar, J. Skidmore, C. Spindloe, E. R. Tubman, N. Woolsey, R. Yurchak, É. Falize

02 Jan 01:12

A self-defense redox mediator for efficient lithium-O2 batteries

Energy Environ. Sci., 2015, Accepted Manuscript
DOI: 10.1039/C5EE02803E, Paper
Tao Zhang, Kaiming Liao, Ping He, HaoShen Zhou
Redox mediators (RMs) have become focal points in rechargeable Li-O2 battery research to reduce overpotentials in oxygen evolution (charge) reactions. In this study, we found an evidence for the shuttle...
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21 Sep 00:08

Ligand-dependent genomic function of glucocorticoid receptor in triple-negative breast cancer

by Zhong Chen

Article

Glucocorticoids are widely used as coadjuvants in the treatment of solid tumours. Here, Chen et al . show that genes regulated by dexamethasone- but not Compound A-liganded glucocorticoid receptor are associated with therapy resistance and unfavourable clinical outcomes in triple-negative breast cancer.

Nature Communications doi: 10.1038/ncomms9323

Authors: Zhong Chen, Xun Lan, Dayong Wu, Benjamin Sunkel, Zhenqing Ye, Jiaoti Huang, Zhihua Liu, Steven K. Clinton, Victor X. Jin, Qianben Wang

06 Sep 14:38

A General Strategy to Fabricate Carbon-Coated 3D Porous Interconnected Metal Sulfides: Case Study of SnS/C Nanocomposite for High-Performance Lithium and Sodium Ion Batteries

by Changbao Zhu, Peter Kopold, Weihan Li, Peter A. van Aken, Joachim Maier, Yan Yu

Transition metal sulfides have a great potential for energy storage due to the pronouncedly higher capacity (owing to conversion to metal or even alloy) than traditional insertion electrode materials. However, the poor cycling stability still limits the development and application in lithium and sodium ion batteries. Here, taking SnS as a model material, a novel general strategy is proposed to fabricate a 3D porous interconnected metal sulfide/carbon nanocomposite by the electrostatic spray deposition technique without adding any expensive carbonaceous materials such as graphene or carbon nanotube. In this way, small nanorods of SnS are generated with sizes of ≈10–20 nm embedded in amorphous carbon and self-assembled into a 3D porous interconnected nanocomposite. The SnS:C is directly deposited on the Ti foil as a current collector and neither conductive additives nor binder are needed for battery assembly. Such electrodes exhibit a high reversible capacity, high rate capability, and long cycling stability for both lithium and sodium storage.

Thumbnail image of graphical abstract

A novel general strategy for fabrication of a 3D porous interconnected metal sulfide/carbon nanocomposite is proposed, using the electrostatic spray deposition technique without adding any expensive carbonaceous materials such as graphene or carbon nanotubes. Such SnS/C composite exhibits a high reversible capacity, high rate capability and long cycling stability for both lithium and sodium storage.

26 Dec 10:46

On ethane ODH mechanism and nature of active sites over NiO-based catalysts via isotopic labeling and methanol sorption studies

Publication date: February 2015
Source:Journal of Catalysis, Volume 322
Author(s): Z. Skoufa , E. Heracleous , A.A. Lemonidou
In this paper, the ethane oxidative dehydrogenation (ODH) mechanism is thoroughly investigated via isotopic labeling and methanol sorption studies over NiO and highly selective Ni0.85Nb0.15O x catalysts. ODH experiments with unlabeled and deuterium labeled ethane demonstrated the existence of strong kinetic isotope effect (KIE) over both NiO and Ni0.85Nb0.15O x , indicating that CH bond scission is the rate determining step in ethane ODH. Similar KIE values obtained for NiO and Ni0.85Nb0.15O x mixed oxide indicate that both catalysts share similar active sites for ethane activation. Methanol adsorption/desorption followed by TGA, MS, and in situ DRIFTS showed that pure and Nb-doped nickel oxide surfaces primarily host the same redox active sites that differ in terms of abundance (i.e. surface concentration) and activity. O2-TPD studies of used catalysts verified the participation of non-stoichiometric oxygen species in the reaction, which proceeds via a redox mechanism. Based on the above, a detailed reaction mechanism is proposed.

Graphical abstract

image
06 Nov 00:01

Lithium-Sulfur Batteries: Dendrite-Free Nanostructured Anode: Entrapment of Lithium in a 3D Fibrous Matrix for Ultra-Stable Lithium–Sulfur Batteries (Small 21/2014)

by Xin-Bing Cheng, Hong-Jie Peng, Jia-Qi Huang, Fei Wei, Qiang Zhang
Thumbnail image of graphical abstract

The entrapment of free-lithium in a 3D fibrous Li7B6 framework produces a LiB nanostructured anode with a stable interface. This structure is demonstrated by Q. Zhang and co-workers on page 4257. The nanostructured anode not only reduces the areal current density that lowers the growth velocity of lithium deposits, but also limits the final size of the deposited lithium, which leads to a dendrite-free morphology at the macroscale.